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CONDENSED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands | 11 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2014 | Dec. 31, 2016 | Dec. 31, 2015
Operating expenses: |  |  |
Research and development | $ 38 | $ 29,356 | $ 11,352
General and administrative | 123 | 7,620 | 2,418
Total operating expenses | 161 | 36,976 | 13,770
Loss from operations | (161) | (36,976) | (13,770)
Change in fair value of convertible preferred stock liability |  |  | (17,600)
Interest income and other expense, net |  | 601 | 35
Net loss | $ (161) | $ (36,375) | $ (31,335)
Net loss per share, basic and diluted (in dollars per share) | $ (0.95) | $ (2.36) | $ (83.86)
Shares used to compute net loss per share, basic and diluted (in shares) | 170,278 | 15,422,041 | 373,643
Other comprehensive income (loss): |  |  |
Unrealized gain (loss) on marketable securities |  | $ 6 | $ (45)
Comprehensive loss | $ (161) | $ (36,369) | $ (31,380)

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