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Stock-Based Compensation (Tables) | 12 Months Ended
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Dec. 31, 2016
Schedule of expenses relating to employee and non-employee stock-based awards | The Company's results of operations include expenses relating to employee and non-employee stock-based awards as follows (in thousands):
|  | Year Ended December 31, 2016 |  | Year Ended December 31, 2015 |  | Period from January 27, 2014 (inception) to December 31, 2014 |
Research and development |  | $ | 1,685 |  | $ | 292 |  | $ | — |
General and administrative |  |  | 2,143 |  |  | 136 |  |  | — |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Total |  | $ | 3,828 |  | $ | 428 |  | $ | — |
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Schedule of fair value of share-based awards to employees was estimated using Black Scholes model |
|  | Year Ended December 31, 2016 |  | Year Ended December 31, 2015 |  | Period from January 27, 2014 (inception) to December 31, 2014 |
Risk-free interest rate |  |  | 1.6 | % |  | 1.7 | % |  | 1.7 | %
Expected volatility |  |  | 84.6 | % |  | 83.3 | % |  | 97.0 | %
Expected term (in years) |  |  | 6 |  |  | 6.1 |  |  | 6.1 |
Expected divident yield |  |  | 0 | % |  | 0 | % |  | 0 | %
Non-employees |
Schedule of fair value of share-based awards to employees was estimated using Black Scholes model |
|  | Year Ended December 31, 2016 |  | Year Ended December 31, 2015
Risk-free interest rate |  | 1.90% - 1.94% |  | 1.8% - 2.2%
Expected volatility |  | 92.1% - 92.7% |  | 82% - 84.7%
Expected term (in years) |  | 8.1 - 8.6 |  | 9.1 - 10.0
Expected divident yield |  | 0% |  | 0%

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- Definition Tabular disclosure of the allocation of equity-based compensation costs to a given line item on the balance sheet and income statement for the period. This may include the reporting line for the costs and the amount capitalized and expensed. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901 + Details
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