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License and Collaboration Agreements (Details) - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Feb. 28, 2017	Feb. 13, 2017
Scripps Research Institute
License and Collaboration Agreements
Milestone payments made	$ 0
Vernalis (R&D) Limited | Subsequent Events
License and Collaboration Agreements
Milestone payments made			$ 3,000,000	$ 0
Licensing Agreement | Scripps Research Institute
License and Collaboration Agreements
Minimum annual fee		$ 25,000
Aggregate potential milestone payments	$ 2,600,000
Period of written notice to terminate	90 days
Licensing Agreement | Scripps Research Institute | Research and development
License and Collaboration Agreements
One-time cash payment		$ 10,000
Licensing Agreement | Vernalis (R&D) Limited
License and Collaboration Agreements
Period of written notice to terminate	90 days
Licensing Agreement | Vernalis (R&D) Limited | Minimum
License and Collaboration Agreements
Aggregate potential milestone payments	$ 200,000,000
Licensing Agreement | Vernalis (R&D) Limited | Research and development
License and Collaboration Agreements
One-time cash payment	$ 1,000,000

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- Definition

The aggregate potential amount of payments the entity may be required to make to the counterparty based on achievement of milestones under the license or collaboration agreement.

+ References

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+ Details

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- Definition

The amount of payments to the entity that are required to be made to the counterparty based on achievement of milestones under the license or collaboration agreement.

+ References

No definition available.

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- Definition

The minimum annual fee the entity is obligated to pay to the counterparty under the license or collaboration agreement.

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- Definition

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- Definition

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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No definition available.

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