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CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022
Operating expenses: |  |  |  |
Research and development | $ 3,965 | $ 10,365 | $ 12,527 | $ 20,388
General and administrative | 1,595 | 2,108 | 5,229 | 6,511
Total operating expenses | 5,560 | 12,473 | 17,756 | 26,899
Loss from operations | (5,560) | (12,473) | (17,756) | (26,899)
Interest income and other expense, net | 425 | 225 | 1,204 | 336
Sublease income - related party |  | 147 | 56 | 439
Loss from equity method investment | (865) | (2,730) | (3,880) | (5,367)
Net loss | $ (6,000) | $ (14,831) | $ (20,376) | $ (31,491)
Net loss per share, basic | $ (0.12) | $ (0.32) | $ (0.43) | $ (0.68)
Net loss per share, diluted | $ (0.12) | $ (0.32) | $ (0.43) | $ (0.68)
Shares used to compute net loss per share, basic | 48,971,246 | 46,553,511 | 47,683,792 | 46,553,511
Shares used to compute net loss per share, diluted | 48,971,246 | 46,553,511 | 47,683,792 | 46,553,511
Other comprehensive loss: |  |  |  |
Unrealized gain (loss) on marketable securities | $ 5 | $ 5 | $ 45 | $ (77)
Cumulative foreign currency translation adjustment | (80) | (1,537) | (925) | (2,985)
Comprehensive loss | $ (6,075) | $ (16,363) | $ (21,256) | $ (34,553)

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