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Equity Method Investment (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2023
Jun. 30, 2023
Mar. 31, 2023
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
Schedule of Equity Method Investments [Line Items]                  
Loss from equity method investment $ 865     $ 2,730     $ 3,880 $ 5,367  
Net loss $ (6,000) $ (6,503) $ (7,873) (14,831) $ (8,363) $ (8,297) $ (20,376) (31,491)  
Angel Pharmaceuticals                  
Schedule of Equity Method Investments [Line Items]                  
Ownership interest (as percent) 49.70%           49.70%   49.70%
Equity reserved (as percent)             7.00%   7.00%
Loss from equity method investment             $ 900   $ (3,900)
Net loss $ (1,016)     (3,204)     (4,565) (6,402)  
Share of loss from investments accounted for using the equity method $ (865)     $ (2,730)     $ (3,880) $ (5,367)