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Related Party Transactions - Additional Information (Details) - USD ($)		3 Months Ended
	Jan. 23, 2026	Mar. 31, 2026	Mar. 31, 2025	Dec. 31, 2025
Related Party Transaction [Line Items]
Research and development		$ 11,175,000	$ 7,453,000
Related party | Support clinical trials | ICON plc
Related Party Transaction [Line Items]
Research and development		$ 123,000	$ 94,000
Angel Pharmaceuticals, Ltd
Related Party Transaction [Line Items]
Equity ownership interest	49.70%	49.70%		49.70%
Follow-on Public Offering
Related Party Transaction [Line Items]
Common shares issued in transaction	9,085,778
Share price of stock issued	$ 22.15
Follow-on Public Offering | Related party | Puissance Capital Management
Related Party Transaction [Line Items]
Common shares issued in transaction	30,000
Share price of stock issued	$ 22.15

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