<?xml version="1.0" encoding="us-ascii"?>
<!-- DFIN ActiveDisclosure(SM) XBRL Schema Document - http://www.dfinsolutions.com/ -->
<!-- Creation Date      : 2021-05-06T14:31:47.4846134+00:00 -->
<!-- Version            : 5.0.1.615 -->
<!-- Package ID         : 09d6c17a41a54e078e65bc95e646e414 -->
<!-- Copyright (c) 2021 Donnelley Financial Solutions, Inc. All Rights Reserved. -->
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  <xsd:element id="fmnb_FinancingReceivableAcquiredLoans" name="FinancingReceivableAcquiredLoans" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFour" name="LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFour" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_ProvisionForCreditLosses" name="ProvisionForCreditLosses" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_ServiceFeesSecurityGainsAndOtherNoninterestIncome" name="ServiceFeesSecurityGainsAndOtherNoninterestIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_NoninterestExpenseExcludingAmortizationAndDepreciation" name="NoninterestExpenseExcludingAmortizationAndDepreciation" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_FederalFundsSoldAndOther" name="FederalFundsSoldAndOther" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_BrokeredTimeDeposits" name="BrokeredTimeDeposits" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_FederalFundsSoldAndOtherInterestIncome" name="FederalFundsSoldAndOtherInterestIncome" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_MergerRelatedCostsIncomes" name="MergerRelatedCostsIncomes" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_CoreProcessingCharge" name="CoreProcessingCharge" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_InsuranceAgencyCommissionsMember" name="InsuranceAgencyCommissionsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_RetirementPlanConsultingFeesMember" name="RetirementPlanConsultingFeesMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_InvestmentCommissionsMember" name="InvestmentCommissionsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_DebitCardAndElectronicFundsTransferFeesMember" name="DebitCardAndElectronicFundsTransferFeesMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_StockIssuedDuringPeriodValueTreasuryStockReissuedUnderLongTermIncentivePlan" name="StockIssuedDuringPeriodValueTreasuryStockReissuedUnderLongTermIncentivePlan" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_SharesIssuedUnderLongTermIncentivePlan" name="SharesIssuedUnderLongTermIncentivePlan" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_CurrentExpectedCreditLossesAdjustment" name="CurrentExpectedCreditLossesAdjustment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_StockIssuedDuringPeriodSharesTreasuryStockReissuedUnderLongTermIncentivePlan" name="StockIssuedDuringPeriodSharesTreasuryStockReissuedUnderLongTermIncentivePlan" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_StockIssuedDuringPeriodSharesUnderLongTermIncentivePlan" name="StockIssuedDuringPeriodSharesUnderLongTermIncentivePlan" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_ProceedsFromSaleOfEquitySecurities" name="ProceedsFromSaleOfEquitySecurities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_PurchaseOfEquitySecurities" name="PurchaseOfEquitySecurities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_PurchaseOfRestrictedStock" name="PurchaseOfRestrictedStock" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_SecurityPurchasesNotSettled" name="SecurityPurchasesNotSettled" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_IssuanceOfStockAwards" name="IssuanceOfStockAwards" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_TroubledDebtRestructuringsTextBlock" name="TroubledDebtRestructuringsTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_AllowanceForCreditLossesAvailableForSaleSecuritiesPolicyTextBlock" name="AllowanceForCreditLossesAvailableForSaleSecuritiesPolicyTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_MapleLeafMember" name="MapleLeafMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_PurchasedCreditImpairedLoansTableTextBlock" name="PurchasedCreditImpairedLoansTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_ScheduleOfAllowanceForLoanLossByPortfolioSegmentTableTextBlock" name="ScheduleOfAllowanceForLoanLossByPortfolioSegmentTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_PaymentDeferralsByLoanTypeOnFinancingReceivablesTableTextBlock" name="PaymentDeferralsByLoanTypeOnFinancingReceivablesTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_InvestmentInResidentialConsumerAndIndirectAutoLoansBasedOnPaymentActivityTableTextBlock" name="InvestmentInResidentialConsumerAndIndirectAutoLoansBasedOnPaymentActivityTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_FinancingReceivableCreditQualityIndicatorsAndYearOfOriginationTableTextBlock" name="FinancingReceivableCreditQualityIndicatorsAndYearOfOriginationTableTextBlock" type="nonnum:textBlockItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_SummaryOfSignificantAccountingPoliciesAdditionalTextualAbstract" name="SummaryOfSignificantAccountingPoliciesAdditionalTextualAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_SummaryOfSignificantAccountingPoliciesLineItems" name="SummaryOfSignificantAccountingPoliciesLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_SummaryOfSignificantAccountingPoliciesTable" name="SummaryOfSignificantAccountingPoliciesTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_FeeIncomeWaived" name="FeeIncomeWaived" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_PercentageOfDecreaseInNetInterestMargin" name="PercentageOfDecreaseInNetInterestMargin" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredSecuritiesAvailableForSale" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredSecuritiesAvailableForSale" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCoreDepositIntangibles" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCoreDepositIntangibles" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_BusinessCombinationRecognizedIdentifiableAssetsAndLiabilitiesDepositsAssumed" name="BusinessCombinationRecognizedIdentifiableAssetsAndLiabilitiesDepositsAssumed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedInterestPayableAndOtherLiabilities" name="BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAccruedInterestPayableAndOtherLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_BusinessAcquisitionsProFormaInterestIncomeExpenseNet" name="BusinessAcquisitionsProFormaInterestIncomeExpenseNet" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_BusinessAcquisitionsProFormaEarningsPerShareBasicAndDiluted" name="BusinessAcquisitionsProFormaEarningsPerShareBasicAndDiluted" type="num:perShareItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_SmallBusinessAdministrationMember" name="SmallBusinessAdministrationMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_ResidentialCollateralizedMortgageObligationsMember" name="ResidentialCollateralizedMortgageObligationsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_DebtSecuritiesAvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValueAbstract" name="DebtSecuritiesAvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValueAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_NumberOfSecurities" name="NumberOfSecurities" type="xbrli:integerItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_NumberOfSecuritiesOnUnrealizedLossPosition" name="NumberOfSecuritiesOnUnrealizedLossPosition" type="xbrli:integerItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_OriginatedLoansMember" name="OriginatedLoansMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_AcquiredLoansMember" name="AcquiredLoansMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CommercialRealEstateOwnerOccupiedMember" name="CommercialRealEstateOwnerOccupiedMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CommercialRealEstateNonOwnerOccupiedMember" name="CommercialRealEstateNonOwnerOccupiedMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CommercialRealEstateFarmlandMember" name="CommercialRealEstateFarmlandMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CommercialRealEstateOtherMember" name="CommercialRealEstateOtherMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CommercialCommercialAndIndustrialMember" name="CommercialCommercialAndIndustrialMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CommercialAgriculturalMember" name="CommercialAgriculturalMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_ResidentialRealEstateOneToFourFamilyResidentialMember" name="ResidentialRealEstateOneToFourFamilyResidentialMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_ResidentialRealEstateHomeEquityMember" name="ResidentialRealEstateHomeEquityMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_ConsumerIndirectMember" name="ConsumerIndirectMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_ConsumerDirectMember" name="ConsumerDirectMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_ConsumerOtherMember" name="ConsumerOtherMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodContractuallyRequiredPaymentsReceivableAtAcquisitionOutstandingBalance" name="CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodContractuallyRequiredPaymentsReceivableAtAcquisitionOutstandingBalance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodContractuallyRequiredPaymentsReceivableAtAcquisitionNetCarryingValue" name="CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodContractuallyRequiredPaymentsReceivableAtAcquisitionNetCarryingValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_NationalBancsharesCorporationMember" name="NationalBancsharesCorporationMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_LoansAndLeasesReceivableAllowanceAdjustedBalance" name="LoansAndLeasesReceivableAllowanceAdjustedBalance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_FinancingReceivableAllowanceForCreditLossesImpactOfCECLAdoption" name="FinancingReceivableAllowanceForCreditLossesImpactOfCECLAdoption" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_FinancingReceivableAllowanceForCreditLossAcquiredLoansCollectivelyEvaluatedForImpairment" name="FinancingReceivableAllowanceForCreditLossAcquiredLoansCollectivelyEvaluatedForImpairment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_FinancingReceivableAllowanceForCreditLossAcquiredWithDeterioratedCreditQuality" name="FinancingReceivableAllowanceForCreditLossAcquiredWithDeterioratedCreditQuality" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_TroubledDebtRestructuringsMember" name="TroubledDebtRestructuringsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CommercialFarmlandMember" name="CommercialFarmlandMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_SmallBusinessAdministrationSBACARESActPaycheckProtectionProgramMember" name="SmallBusinessAdministrationSBACARESActPaycheckProtectionProgramMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_FirstRoundOfPaycheckProtectionProgramLoanMember" name="FirstRoundOfPaycheckProtectionProgramLoanMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_SecondRoundOfPaycheckProtectionProgramLoanMember" name="SecondRoundOfPaycheckProtectionProgramLoanMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_DebtInstrumentMaturityDateLengthOfExtensionPeriod" name="DebtInstrumentMaturityDateLengthOfExtensionPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_DebtInstrumentInterestRateReductionPercentage" name="DebtInstrumentInterestRateReductionPercentage" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_FinancingReceivablePeriodOfModifiedContractuallyPastDueLoansToBeConsideredAsPaymentDefault" name="FinancingReceivablePeriodOfModifiedContractuallyPastDueLoansToBeConsideredAsPaymentDefault" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_ProvisionReversalForLoanLossesExpensed" name="ProvisionReversalForLoanLossesExpensed" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_NumberOfMonthsOfferedForDeferralPayments" name="NumberOfMonthsOfferedForDeferralPayments" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_NumberOfBusinessCustomers" name="NumberOfBusinessCustomers" type="xbrli:integerItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_PaymentsReceivedFromForgivenessOfLoans" name="PaymentsReceivedFromForgivenessOfLoans" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_PercentageOfPaymentsReceivedFromForgivenessOfLoans" name="PercentageOfPaymentsReceivedFromForgivenessOfLoans" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_CommercialLoanAndCommercialRealEstateRiskMaximum" name="CommercialLoanAndCommercialRealEstateRiskMaximum" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_CommercialAndIndustrialMember" name="CommercialAndIndustrialMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_AgriculturalPortfolioSegmentMember" name="AgriculturalPortfolioSegmentMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_HomeEquityLinesOfCreditMember" name="HomeEquityLinesOfCreditMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_TrustSegmentMember" name="TrustSegmentMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_BankSegmentMember" name="BankSegmentMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_ContingentFeesAndCommissionsDebitCardsReceivable" name="ContingentFeesAndCommissionsDebitCardsReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_RevenueFromContractWithCustomerLineItems" name="RevenueFromContractWithCustomerLineItems" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_RevenueFromContractWithCustomerTable" name="RevenueFromContractWithCustomerTable" type="xbrli:stringItemType" substitutionGroup="xbrldt:hypercubeItem" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CeteraMember" name="CeteraMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_ContingentFeesAndCommissionsFiduciaryAndTrustActivitiesReceivable" name="ContingentFeesAndCommissionsFiduciaryAndTrustActivitiesReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_ContingentInsuranceCommissionsAndFeesReceivable" name="ContingentInsuranceCommissionsAndFeesReceivable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_PercentageOfInsuranceCommissionsOnRevenues" name="PercentageOfInsuranceCommissionsOnRevenues" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_PercentageOfRetirementPlanConsultingFeesOnRevenues" name="PercentageOfRetirementPlanConsultingFeesOnRevenues" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_ContingentBrokerageCommissionsRevenuePayable" name="ContingentBrokerageCommissionsRevenuePayable" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_PercentageOfInvestmentCommissionsOnRevenues" name="PercentageOfInvestmentCommissionsOnRevenues" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_AvailableForSaleSecuritiesDebtAndEquity" name="AvailableForSaleSecuritiesDebtAndEquity" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_FairValueAssetsAndLiabilitiesLevel1AndLevel2TransfersAmount" name="FairValueAssetsAndLiabilitiesLevel1AndLevel2TransfersAmount" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_CollateralDependentLoansMember" name="CollateralDependentLoansMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_CollateralDependentImpairedLoansMember" name="CollateralDependentImpairedLoansMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetPeriodIncrease" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetPeriodIncrease" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetRepaymentsCallsAndMaturities" name="FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisAssetRepaymentsCallsAndMaturities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_CollateralFinancingReceivableRecordedInvestment" name="CollateralFinancingReceivableRecordedInvestment" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_CollateralFinancingReceivableWithRelatedAllowanceUnpaidPrincipalBalance" name="CollateralFinancingReceivableWithRelatedAllowanceUnpaidPrincipalBalance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_CollateralFinancingReceivableRelatedAllowance" name="CollateralFinancingReceivableRelatedAllowance" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_CashCashEquivalentsAndFederalFundsSoldFairValue" name="CashCashEquivalentsAndFederalFundsSoldFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_AccruedInterestReceivableFairValue" name="AccruedInterestReceivableFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_AccruedInterestPayableFairValue" name="AccruedInterestPayableFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_MaximumMaturityPeriodOfShortTermBorrowings" name="MaximumMaturityPeriodOfShortTermBorrowings" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFour" name="FiniteLivedIntangibleAssetsAmortizationExpenseAfterYearFour" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="debit" />
  <xsd:element id="fmnb_OperatingLeaseAndFinancingLeaseWeightedAverageRemainingLeaseTerm" name="OperatingLeaseAndFinancingLeaseWeightedAverageRemainingLeaseTerm" type="xbrli:durationItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="false" />
  <xsd:element id="fmnb_LesseeOperatingLeaseAndFinancingLeaseDiscountRate" name="LesseeOperatingLeaseAndFinancingLeaseDiscountRate" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_WeightedAveragePayRateOnInterestRateSwaps" name="WeightedAveragePayRateOnInterestRateSwaps" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_WeightedAverageInterestRateReceivedInterestRateSwaps" name="WeightedAverageInterestRateReceivedInterestRateSwaps" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_TwoThousandAndSeventeenIncentivePlanMember" name="TwoThousandAndSeventeenIncentivePlanMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_TimeBasedRestrictedStockAwardsMember" name="TimeBasedRestrictedStockAwardsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_PerformanceBasedRestrictedStockAwardsMember" name="PerformanceBasedRestrictedStockAwardsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_RegulatoryMattersAdditionalTextualAbstract" name="RegulatoryMattersAdditionalTextualAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_TierOneRiskBasedCommonCapitalRequiredForCapitalAdequacyToRiskWeightedAssetsCapitalConservationBufferRatio" name="TierOneRiskBasedCommonCapitalRequiredForCapitalAdequacyToRiskWeightedAssetsCapitalConservationBufferRatio" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_TierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssetsCapitalConservationBufferRatio" name="TierOneRiskBasedCapitalRequiredForCapitalAdequacyToRiskWeightedAssetsCapitalConservationBufferRatio" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_CapitalRequiredForCapitalAdequacyToRiskWeightedAssetsCapitalConservationBufferRatio" name="CapitalRequiredForCapitalAdequacyToRiskWeightedAssetsCapitalConservationBufferRatio" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_TierOneRiskBasedCommonCapitalRequiredForCapitalAdequacyToRiskWeightedAssets" name="TierOneRiskBasedCommonCapitalRequiredForCapitalAdequacyToRiskWeightedAssets" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_TierOneCommonCapitalRatioAbstract" name="TierOneCommonCapitalRatioAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_TierOneCommonCapital" name="TierOneCommonCapital" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_TierOneCommonCapitalRatio" name="TierOneCommonCapitalRatio" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_TierOneRiskBasedCommonCapitalRequiredForCapitalAdequacy" name="TierOneRiskBasedCommonCapitalRequiredForCapitalAdequacy" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_TierOneRiskBasedCommonCapitalRequiredToBeWellCapitalized" name="TierOneRiskBasedCommonCapitalRequiredToBeWellCapitalized" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
  <xsd:element id="fmnb_TierOneRiskBasedCommonCapitalRequiredToBeWellCapitalizedToRiskWeightedAssets" name="TierOneRiskBasedCommonCapitalRequiredToBeWellCapitalizedToRiskWeightedAssets" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_EliminationsAndReconcilingItemsMember" name="EliminationsAndReconcilingItemsMember" type="nonnum:domainItemType" substitutionGroup="xbrli:item" xbrli:periodType="duration" nillable="true" abstract="true" />
  <xsd:element id="fmnb_NumberOfLendingInstitutions" name="NumberOfLendingInstitutions" type="xbrli:integerItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_PledgedSecuritiesPercentageOfRepurchaseAgreementBalances" name="PledgedSecuritiesPercentageOfRepurchaseAgreementBalances" type="num:percentItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" />
  <xsd:element id="fmnb_AdditionalFederalHomeLoanBankAdvancesToBeBorrowUnderCollateralPledge" name="AdditionalFederalHomeLoanBankAdvancesToBeBorrowUnderCollateralPledge" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" xbrli:periodType="instant" nillable="true" abstract="false" xbrli:balance="credit" />
</xsd:schema>
