<SEC-DOCUMENT>0001140361-15-037104.txt : 20151007
<SEC-HEADER>0001140361-15-037104.hdr.sgml : 20151007
<ACCEPTANCE-DATETIME>20151007180052
ACCESSION NUMBER:		0001140361-15-037104
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20151007
FILED AS OF DATE:		20151007
DATE AS OF CHANGE:		20151007

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CytomX Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001501989
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		650 GATEWAY BLVD.
		STREET 2:		SUITE 125
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080
		BUSINESS PHONE:		650.515.3185

	MAIL ADDRESS:	
		STREET 1:		650 GATEWAY BLVD.
		STREET 2:		SUITE 125
		CITY:			SOUTH SAN FRANCISCO
		STATE:			CA
		ZIP:			94080

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SHANNON TIMOTHY M
		CENTRAL INDEX KEY:			0001207114

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37587
		FILM NUMBER:		151149748

	MAIL ADDRESS:	
		STREET 1:		C/O CURAGEN CORP
		STREET 2:		555LONG WHARF DR. 11TH FL.
		CITY:			NEW HAVEN
		STATE:			CT
		ZIP:			06511
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
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<DESCRIPTION>FORM 3
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    <documentType>3</documentType>

    <periodOfReport>2015-10-07</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001501989</issuerCik>
        <issuerName>CytomX Therapeutics, Inc.</issuerName>
        <issuerTradingSymbol>CTMX</issuerTradingSymbol>
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    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001207114</rptOwnerCik>
            <rptOwnerName>SHANNON TIMOTHY M</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>285 RIVERSIDE AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 250</rptOwnerStreet2>
            <rptOwnerCity>WESTPORT</rptOwnerCity>
            <rptOwnerState>CT</rptOwnerState>
            <rptOwnerZipCode>06880</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
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            <otherText></otherText>
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    </reportingOwner>

    <nonDerivativeTable></nonDerivativeTable>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Series B-1 Convertible Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <exerciseDate>
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            </exerciseDate>
            <expirationDate>
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                <underlyingSecurityTitle>
                    <value>Common Stock</value>
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                <underlyingSecurityShares>
                    <value>3566337</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By Canaan IX L.P.</value>
                    <footnoteId id="F2"/>
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        <derivativeHolding>
            <securityTitle>
                <value>Series C Convertible Preferred Stock</value>
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                    <value>By Canaan IX L.P.</value>
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        <footnote id="F1">Each of the Series B-1 Convertible Preferred Stock and the Series C Convertible Preferred Stock is convertible at any time at the option of the holder (and is automatically convertible upon closing of the Issuer's initial public offering of its Common Stock) into Common Stock on a one-for-one basis, for no additional consideration, and has no expiration date.</footnote>
        <footnote id="F2">These shares are held directly by Canaan IX L.P.  The Reporting Person is a non-managing member of Canaan Partners IX LLC, the general partner of Canaan IX L.P.  The Reporting Person does not have voting, investment or dispositive power over any of the shares directly held by Canaan IX L.P. and disclaims beneficial ownership of the shares except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of the shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.</footnote>
    </footnotes>

    <remarks>Exhibit 24.1 - Power of Attorney</remarks>

    <ownerSignature>
        <signatureName>/s/ Cynthia J. Ladd, attorney-in-fact</signatureName>
        <signatureDate>2015-10-07</signatureDate>
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<div style="MARGIN-LEFT: 0pt; MARGIN-RIGHT: 0pt; TEXT-INDENT: 0pt" align="justify"><font style="FONT-SIZE: 10pt; FONT-FAMILY: Times New Roman; DISPLAY: inline">execute for and on behalf of the undersigned, in the undersigned's capacity as an officer and/or director of <font style="TEXT-DECORATION: underline; DISPLAY: inline">CytomX Therapeutics, Inc</font>. (the "Company"), Forms 3, 4, and 5 in accordance with Section 16(a) of the Securities Exchange Act of 1934 and the rules thereunder;</font></div>
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