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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2022
Income Tax Disclosure [Abstract] |
Schedule of Effective Tax Rate Reconciliation | A reconciliation of the Company’s effective tax rate to the statutory U.S. federal rate is as follows:
|  | Years Ended December 31, |
|  | 2022 |  |  | 2021 |
U.S. federal taxes at statutory rate |  |  | 21.0 | % |  |  | 21.0 | %
State tax, net of federal benefit |  |  | 1.7 | % |  |  | 1.5 | %
Stock compensation |  |  | (2.1 | )% |  |  | (3.1 | )%
Tax credits |  |  | 2.4 | % |  |  | 2.0 | %
Change in valuation allowance |  |  | (22.8 | )% |  |  | (21.4 | )%
162(m) limitation |  |  | (0.2 | )% |  |  | 0.0 | %
Total |  |  | 0.0 |  |  |  | 0.0 |
Schedule of Deferred Income Tax Assets and Liabilities | The types of temporary differences that give rise to significant portions of the Company’s deferred income tax assets and liabilities are set out below (in thousands):
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
Net operating loss carryforwards |  | $ | 58,193 |  |  | $ | 49,070 |
Research and development credits |  |  | 24,700 |  |  |  | 20,809 |
Lease liability |  |  | 3,802 |  |  |  | 4,555 |
Intangible assets |  |  | 3,708 |  |  |  | 3,804 |
Deferred revenue |  |  | 49,919 |  |  |  | 60,285 |
Accrued liabilities |  |  | 1,504 |  |  |  | 1,933 |
Stock-based compensation |  |  | 8,066 |  |  |  | 7,480 |
Sec 174 capitalized research and development costs |  |  | 19,709 |  |  | — |
Other |  |  | 31 |  |  |  | 29 |
Total gross deferred income tax assets |  |  | 169,632 |  |  |  | 147,965 |
Less: valuation allowance |  |  | (166,037 | ) |  |  | (143,355 | )
Deferred tax assets, net of valuation allowance |  |  | 3,595 |  |  |  | 4,610 |
Fixed assets |  |  | (43 | ) |  |  | (253 | )
Right-of-use assets |  |  | (3,358 | ) |  |  | (4,069 | )
Prepaid expenses |  |  | (194 | ) |  |  | (288 | )
Deferred tax liabilities |  |  | (3,595 | ) |  |  | (4,610 | )
Net deferred income tax liabilities |  | $ | — |  |  | $ | — |
Schedule of Reconciliation of Unrecognized Tax Benefits | A reconciliation of the beginning and ending unrecognized tax benefit amount is as follows (in thousands):
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |
Balance at the beginning of the year |  | $ | 7,780 |  |  | $ | 6,454 |
Additions based on tax positions related to current year |  |  | 1,391 |  |  |  | 1,326 |
Adjustment based on tax positions related to prior years |  |  | 98 |  |  |  | - |
Balance at end of the year |  | $ | 9,269 |  |  | $ | 7,780 |

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- Definition Tabular disclosure of the components of net deferred tax asset or liability recognized in an entity's statement of financial position, including the following: the total of all deferred tax liabilities, the total of all deferred tax assets, the total valuation allowance recognized for deferred tax assets. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 2 -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32537-109319 + Details
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- Definition Tabular disclosure of the reconciliation using percentage or dollar amounts of the reported amount of income tax expense attributable to continuing operations for the year to the amount of income tax expense that would result from applying domestic federal statutory tax rates to pretax income from continuing operations. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 12 -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32687-109319 + Details
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- Definition Tabular disclosure for tax positions taken in the tax returns filed or to be filed for which it is more likely than not that the tax position will not be sustained upon examination by taxing authorities and other income tax contingencies. Includes, but is not limited to, interest and penalties, reconciliation of unrecognized tax benefits, unrecognized tax benefits that would affect the effective tax rate, tax years that remain subject to examination by tax jurisdictions, and information about positions for which it is reasonably possible that amounts unrecognized will significantly change within 12 months. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 15A -URI https://asc.fasb.org/extlink&oid=121826272&loc=SL6600010-109319 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 15 -Subparagraph (d) -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32718-109319 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 740 -SubTopic 10 -Section 50 -Paragraph 19 -URI https://asc.fasb.org/extlink&oid=121826272&loc=d3e32840-109319 + Details
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