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Collaboration and License Agreements - AbbVie Ireland Unlimited Company - Additional Information (Details)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended 12 Months Ended
Dec. 31, 2022
USD ($)
Mar. 31, 2020
USD ($)
Jun. 30, 2019
USD ($)
May 31, 2018
USD ($)
Jul. 31, 2017
USD ($)
Apr. 30, 2016
USD ($)
AccountingUnit
Agreement
Target
Sep. 30, 2022
USD ($)
Jun. 30, 2022
USD ($)
Mar. 31, 2022
USD ($)
Jun. 30, 2022
USD ($)
Sep. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Dec. 31, 2020
USD ($)
Mar. 31, 2017
Target
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Revenue recognized             $ 11,147 $ 12,853 $ 9,040 $ 21,893 $ 33,040 $ 53,163 $ 37,312    
Type of Revenue [Extensible List]                       us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember    
Deferred revenue $ 301,326                     $ 301,326 $ 284,760 $ 318,707  
AbbVie Ireland Unlimited Company                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Revenue recognized   $ 26,600   $ 9,900     $ 2,972 $ 6,775 $ 1,751 $ 8,526 $ 11,498        
AbbVie Ireland Unlimited Company | ASC 606                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Upfront payment received           $ 30,000                  
Milestone payment received           14,000                  
Total transaction price           39,800                  
Estimated sublicense fees           $ 4,200                  
Number of accounting units | AccountingUnit           2                  
AbbVie Ireland Unlimited Company | Second Target                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Change in estimated collaboration amount 4,400                            
AbbVie Ireland Unlimited Company | Collaborative Arrangement                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Number of collaboration agreements | Agreement           2                  
Percentage of net profits or net losses related to development and commercialization costs           35.00%                  
AbbVie Ireland Unlimited Company | CD71 Agreement                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Upfront payment received           $ 20,000           100,000      
Milestone payments received   40,000   21,000 $ 14,000             100,000      
Total transaction price           29,800                  
Milestone payment received   $ 40,000   21,000                      
Deferred revenue 4,000                     4,000 16,100    
AbbVie Ireland Unlimited Company | CD71 Agreement | Transferred over Time                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Type of Revenue [Extensible List]   us-gaap:LicenseAndServiceMember                          
AbbVie Ireland Unlimited Company | CD71 Agreement | ASC 606                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Upfront payment received           20,000                  
Estimated sublicense fees           4,200                  
Milestone payment received           $ 14,000                  
AbbVie Ireland Unlimited Company | CD71 Agreement | U.S                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Profit split on U.S. sales           35.00%                  
AbbVie Ireland Unlimited Company | CD71 Agreement | Maximum                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Contingent payments receivable upon achieving development, regulatory and commercial milestones           $ 470,000                  
AbbVie Ireland Unlimited Company | Seattle Genetics Agreement                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Sublicense fees paid       $ 4,000 $ 1,000                    
AbbVie Ireland Unlimited Company | Seattle Genetics Agreement | ASC 606                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Sublicense fees paid           1,000                  
AbbVie Ireland Unlimited Company | Discovery Agreement                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Upfront payment received           10,000                  
Number of targets selected | Target                             1
Total transaction price           10,000                  
Deferred revenue $ 0                     $ 0 $ 6,500    
AbbVie Ireland Unlimited Company | Discovery Agreement | ASC 606                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Upfront payment received           10,000                  
AbbVie Ireland Unlimited Company | Discovery Agreement | Second Target                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Milestone payments received     $ 10,000     $ 10,000                  
AbbVie Ireland Unlimited Company | Discovery Agreement | Second Target | ASC 606                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Total transaction price     $ 10,000                        
Estimated research service period     5 years                        
AbbVie Ireland Unlimited Company | Discovery Agreement | Maximum                              
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                              
Number of targets | Target           2