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Collaboration and License Agreements - Astellas Pharma Inc - Additional Information (Details) $ in Thousands |  | 1 Months Ended | 3 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | ---
Mar. 23, 2020 USD ($) Target | Jan. 31, 2023 USD ($) | Mar. 31, 2025 USD ($) | Mar. 31, 2024 USD ($) | Dec. 31, 2024 USD ($) | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Deferred revenue |  |  |  |  | $ 94,063 | $ 212,315 | $ 301,326
Astellas Pharma Inc. |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Deferred revenue |  |  |  |  | 17,400 |  |
Collaboration and License Agreement | Astellas Pharma Inc. |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Number of targets selected | Target | 1 |  |  |  |  |  |
Number of additional collaboration target | Target | 3 |  |  |  |  |  |
Upfront payment received | $ 80,000 |  |  |  |  |  |
Total transaction price | 103,200 |  |  |  |  |  |
Research and development service fees | $ 23,200 |  |  |  |  |  |
Milestone payments received |  | $ 5,000 |  | $ 5,000 |  |  |
Additional milestone payment received |  |  |  | $ 5,000 |  |  |
Deferred revenue |  |  |  |  | 17,400 | 31,000 |
Amount due from customer |  |  |  |  | $ 1,100 | $ 2,200 |
Collaboration and License Agreement | Astellas Pharma Inc. | Forecast |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Milestone payments received |  |  | $ 5,000 |  |  |  |
Collaboration and License Agreement | Astellas Pharma Inc. | Maximum |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Number of targets | Target | 4 |  |  |  |  |  |
Right to expand the number of additional collaboration target | Target | 5 |  |  |  |  |  |
Contingent milestone payments receivable | $ 1,600,000 |  |  |  |  |  |
Collaboration and License Agreement | Astellas Pharma Inc. | Minimum |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |
Right to expand the number of additional collaboration target | Target | 3 |  |  |  |  |  |

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