XML 64 R54.htm IDEA: XBRL DOCUMENT v3.25.0.1

Collaboration and License Agreements - Amgen, Inc - Additional Information (Details) $ / shares in Units, $ in Thousands		1 Months Ended	3 Months Ended		12 Months Ended
	Sep. 29, 2017 USD ($) Target	Oct. 31, 2017 USD ($) $ / shares shares	Jun. 30, 2020	Jun. 30, 2019	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Common stock, value of shares issued in connection with agreement					$ 6,909
Deferred revenue					94,063	$ 212,315	$ 301,326
Amgen Inc | EGFR Products
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue					9,700
Collaboration and License Agreement | Amgen Inc
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Upfront payment received	$ 40,000	$ 40,000
Common stock, shares issuable under agreement | shares		1,156,069
Common stock, shares issuable under agreement, price per share | $ / shares		$ 17.3
Common stock, value of shares issued in connection with agreement		$ 20,000
Number of targets selected | Target	1
Number of additional collaboration target | Target	2
Total transaction price	$ 51,200
Portion of transaction price allocated to premium on sale of common stock	500
Estimated fair value of products	10,700
Collaboration and License Agreement | Amgen Inc | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contingent payments payable	203,000
Collaboration and License Agreement | Amgen Inc | EGFR Products
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total transaction price	46,400
Estimated research service period			7 years	8 years
Deferred revenue					$ 9,700	$ 12,800
Collaboration and License Agreement | Amgen Inc | EGFR Products | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contingent milestone payments receivable	$ 460,000
Percentage share of profit and losses	50.00%
Collaboration and License Agreement | Amgen Inc | Amgen Products | Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Contingent milestone payments receivable	$ 950,000
Number of targets | Target	3
Collaboration and License Agreement | Amgen Inc | Amgen Other Products
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Total transaction price	$ 4,800
Estimated research service period	6 years
Revenue recognition upon performance obligation	$ 4,800
Sublicense Agreement | Amgen Inc | Maximum | UC Regents
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Sublicense payment percentage	7.50%

X

- Definition

Aggregate collaboration transaction amount.

+ References

No definition available.

+ Details

Name:	ctmx_AggregateCollaborationTransactionAmount
Namespace Prefix:	ctmx_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- Definition

Common stock shares issuable under agreement.

+ References

No definition available.

+ Details

Name:	ctmx_CommonStockSharesIssuableUnderAgreement
Namespace Prefix:	ctmx_
Data Type:	xbrli:sharesItemType
Balance Type:	na
Period Type:	instant

X

- Definition

Future contingent milestone payment receivable.

+ References

No definition available.

+ Details

Name:	ctmx_ContingentMilestonePaymentsReceivable
Namespace Prefix:	ctmx_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

X

- Definition

Contingent payments payable upon achieving development regulatory and commercial milestones.

+ References

No definition available.

+ Details

Name:	ctmx_ContingentPaymentsPayableUponAchievingDevelopmentRegulatoryAndCommercialMilestones
Namespace Prefix:	ctmx_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- Definition

Estimated fair value of products.

+ References

No definition available.

+ Details

Name:	ctmx_EstimatedFairValueOfProducts
Namespace Prefix:	ctmx_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	instant

X

- Definition

Estimated research service period.

+ References

No definition available.

+ Details

Name:	ctmx_EstimatedResearchServicePeriod
Namespace Prefix:	ctmx_
Data Type:	xbrli:durationItemType
Balance Type:	na
Period Type:	duration

X

- Definition

License payment percentage equivalence to upfront and milestone proceeds.

+ References

No definition available.

+ Details

Name:	ctmx_LicensePaymentPercentageEquivalenceToUpfrontAndMilestoneProceeds
Namespace Prefix:	ctmx_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Number of additional collaboration target.

+ References

No definition available.

+ Details

Name:	ctmx_NumberOfAdditionalCollaborationTarget
Namespace Prefix:	ctmx_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	instant

X

- Definition

Number of targets.

+ References

No definition available.

+ Details

Name:	ctmx_NumberOfTargets
Namespace Prefix:	ctmx_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	instant

X

- Definition

Number of targets selected.

+ References

No definition available.

+ Details

Name:	ctmx_NumberOfTargetsSelected
Namespace Prefix:	ctmx_
Data Type:	xbrli:integerItemType
Balance Type:	na
Period Type:	instant

X

- Definition

Premium on issuance of shares allocated to common stock.

+ References

No definition available.

+ Details

Name:	ctmx_PremiumOnIssuanceOfSharesAllocatedToCommonStock
Namespace Prefix:	ctmx_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

X

- Definition

Profit share upon exercise of co-development option.

+ References

No definition available.

+ Details

Name:	ctmx_ProfitShareUponExerciseOfCoDevelopmentOption
Namespace Prefix:	ctmx_
Data Type:	dtr-types:percentItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 808
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 1
-Subparagraph (d)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479402/808-10-50-1

+ Details

Name:	us-gaap_CollaborativeArrangementsAndNoncollaborativeArrangementTransactionsLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 45
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479837/606-10-45-1

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 8
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-8

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 45
-Paragraph 2
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479837/606-10-45-2

+ Details

Name:	us-gaap_ContractWithCustomerLiability
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- Definition

Cash received from collaborators during the current period.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Topic 230
-SubTopic 10
-Name Accounting Standards Codification
-Section 45
-Paragraph 25
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482740/230-10-45-25

+ Details

Name:	us-gaap_ProceedsFromCollaborators
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

X

- Definition

The cash inflow from the additional capital contribution to the entity.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Section 45
-Paragraph 14
-Subparagraph (a)
-SubTopic 10
-Topic 230
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482740/230-10-45-14

+ Details

Name:	us-gaap_ProceedsFromIssuanceOfCommonStock
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

X

- Definition

Amount of transaction price allocated to performance obligation that has not been recognized as revenue.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Name Accounting Standards Codification
-Section 50
-Paragraph 13
-Subparagraph (a)
-SubTopic 10
-Topic 606
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-13

+ Details

Name:	us-gaap_RevenueRemainingPerformanceObligation
Namespace Prefix:	us-gaap_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	instant

X

- Definition

Price of a single share of a number of saleable stocks of a company.

+ References

No definition available.

+ Details

Name:	us-gaap_SharePrice
Namespace Prefix:	us-gaap_
Data Type:	dtr-types:perShareItemType
Balance Type:	na
Period Type:	instant

X

- Details

Name:	srt_CounterpartyNameAxis=ctmx_AmgenIncMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	srt_ProductOrServiceAxis=ctmx_EGFRProductsMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	us-gaap_TypeOfArrangementAxis=ctmx_CollaborationAndLicenseAgreementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	srt_RangeAxis=srt_MaximumMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	srt_ProductOrServiceAxis=ctmx_AmgenProductsMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	srt_ProductOrServiceAxis=ctmx_AmgenOtherProductsMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	us-gaap_TypeOfArrangementAxis=ctmx_SublicenseAgreementMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

X

- Details

Name:	us-gaap_ResearchAndDevelopmentArrangementContractToPerformForOthersByTypeAxis=ctmx_RegentsOfTheUniversityOfCaliforniaMember
Namespace Prefix:
Data Type:	na
Balance Type:
Period Type: