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Aggregate collaboration transaction amount.

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Future contingent milestone payment receivable.

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Milestone payment received.

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Number of additional collaboration target.

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Number of targets.

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Number of targets selected.

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Research and development service fees.

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Right to expand the number of additional collaboration target.

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Collaboration and License Agreements - Astellas Pharma Inc - Additional Information (Details) $ in Thousands		1 Months Ended	3 Months Ended
	Mar. 23, 2020 USD ($) Target	Jan. 31, 2023 USD ($)	Mar. 31, 2025 USD ($)	Mar. 31, 2024 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue					$ 94,063	$ 212,315	$ 301,326
Astellas Pharma Inc.
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Deferred revenue					17,400
Collaboration and License Agreement \| Astellas Pharma Inc.
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of targets selected \| Target	1
Number of additional collaboration target \| Target	3
Upfront payment received	$ 80,000
Total transaction price	103,200
Research and development service fees	$ 23,200
Milestone payments received		$ 5,000		$ 5,000
Additional milestone payment received				$ 5,000
Deferred revenue					17,400	31,000
Amount due from customer					$ 1,100	$ 2,200
Collaboration and License Agreement \| Astellas Pharma Inc. \| Forecast
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Milestone payments received			$ 5,000
Collaboration and License Agreement \| Astellas Pharma Inc. \| Maximum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of targets \| Target	4
Right to expand the number of additional collaboration target \| Target	5
Contingent milestone payments receivable	$ 1,600,000
Collaboration and License Agreement \| Astellas Pharma Inc. \| Minimum
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Right to expand the number of additional collaboration target \| Target	3