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Share-based payments - Movements in the weighted average exercise price of share options (Details) - £ / shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Share-based payments    
Weighted average exercise price, options outstanding, start of period £ 143.28  
Granted during the period 1,178.94 £ 143.28
Forfeited during the period 204.00  
Weighted average exercise price, options outstanding, end of period £ 308.06 £ 143.28