<SEC-DOCUMENT>0001104659-19-032915.txt : 20190530
<SEC-HEADER>0001104659-19-032915.hdr.sgml : 20190530
<ACCEPTANCE-DATETIME>20190530212610
ACCESSION NUMBER:		0001104659-19-032915
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20190528
FILED AS OF DATE:		20190530
DATE AS OF CHANGE:		20190530

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			BINGHAM KATE
		CENTRAL INDEX KEY:			0001185040

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-38916
		FILM NUMBER:		19868372

	MAIL ADDRESS:	
		STREET 1:		1365 MAIN STREET
		CITY:			WALTHAM
		STATE:			MA
		ZIP:			02451

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BICYCLE THERAPEUTICS plc
		CENTRAL INDEX KEY:			0001761612
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000

	BUSINESS ADDRESS:	
		STREET 1:		B900 BABRAHAM RESEARCH CAMPUS
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3AT
		BUSINESS PHONE:		011441223261503

	MAIL ADDRESS:	
		STREET 1:		B900 BABRAHAM RESEARCH CAMPUS
		CITY:			CAMBRIDGE
		STATE:			X0
		ZIP:			CB22 3AT

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BICYCLE THERAPEUTICS Ltd
		DATE OF NAME CHANGE:	20181212
</SEC-HEADER>
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<SEQUENCE>1
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                <value></value>
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                </transactionPricePerShare>
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                    <footnoteId id="F1"/>
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                <footnoteId id="F1"/>
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                    <value>D</value>
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    <footnotes>
        <footnote id="F1">Each Series A and B1 Preferred Share automatically converted into Ordinary Shares on a one-for-1.429 basis upon the closing of the Issuer's initial public offering and had no expiration date.</footnote>
        <footnote id="F2">These shares are owned directly by SV Life Sciences Fund V, L.P. (&quot;SVLS V LP&quot;). SV Life Sciences Fund V (GP), LP (&quot;SVLS V GP&quot;) is the general partner of SVLS V LP. The general partner of SVLS V GP is SVLSF V, LLC. Kate Bingham, Eugene D. Hill, III and Michael J. Ross are members of the investment committee of SVLSF V, LLC. SVLS V GP, SVLSF V, LLC and each of the individuals comprising the SVLSF V, LLC investment committee may be deemed to share voting, dispositive and investment power over the shares held of record by SVLS V LP. Each of SVLS V GP, SVLSF V, LLC and the individual members of the SVLSF V, LLC investment committee disclaims beneficial ownership of these securities and this report shall not be deemed to be an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or any other purpose, except to the extent of their pecuniary interest therein.</footnote>
        <footnote id="F3">These shares are owned directly by SV Life Sciences Fund V Strategic Partners, L.P. (&quot;SVLS V SPP&quot;). SVLS V GP is the general partner of SVLS V SPP. The general partner of SVLS V GP is SVLSF V, LLC. Kate Bingham, Eugene D. Hill, III and Michael J. Ross are members of the investment committee of SVLSF V, LLC. SVLS V GP, SVLSF V, LLC and each of the individuals comprising the SVLSF V, LLC investment committee may be deemed to share voting, dispositive and investment power over the shares held of record by SVLS V SPP. Each of SVLS V GP, SVLSF V, LLC and the individual members of the SVLSF V, LLC investment committee disclaims beneficial ownership of these securities and this report shall not be deemed to be an admission that any one of them is the beneficial owner of such securities for purposes of Section 16 or any other purpose, except to the extent of their pecuniary interest therein</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Lee Kalowski, as Attorney-in-Fact</signatureName>
        <signatureDate>2019-05-30</signatureDate>
    </ownerSignature>
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