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Significant agreements - Collaboration revenues (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2020 | Jun. 30, 2019 | Jun. 30, 2020 | Jun. 30, 2019
Significant agreements. |  |  |  |
Collaboration revenues | $ 1,571 | $ 1,522 | $ 2,700 | $ 7,906
AstraZeneca |  |  |  |
Significant agreements. |  |  |  |
Collaboration revenues | 319 | 362 | 731 | 787
Sanofi |  |  |  |
Significant agreements. |  |  |  |
Collaboration revenues | 0 | 57 | 0 | 6,016
Dementia Discovery Fund |  |  |  |
Significant agreements. |  |  |  |
Collaboration revenues | 56 | 103 | 112 | 103
Material transfer agreement |  |  |  |
Significant agreements. |  |  |  |
Collaboration revenues | 0 | 1,000 |  | $ 1,000
Genetech |  |  |  |
Significant agreements. |  |  |  |
Collaboration revenues | $ 1,196 | $ 0 | $ 1,857 |

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- Definition Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 4 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=118956577&loc=SL49130543-203045 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 606 -SubTopic 10 -Section 50 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=118956577&loc=SL49130545-203045 + Details
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