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Significant agreements - Ionis Share Purchase Agreement (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 3 Months Ended |
--- | --- | --- | ---
Jul. 09, 2021 | Jun. 30, 2024 | Sep. 30, 2023 | Jun. 30, 2023 | Mar. 31, 2023 | Mar. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Aggregate purchase price |  | $ 544,127 | $ 234,492 | $ 12,127 | $ 2,716 |
Ionis |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Transaction price | $ 38,000 |  |  |  |  | $ 37,800
Ionis | Ionis Share Purchase Agreement |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Shares issued (in shares) | 282,485 |  |  |  |  |
Purchase price per share | $ 38.94 |  |  |  |  |
Aggregate purchase price | $ 11,000 |  |  |  |  |
Fair value of shares held | 7,600 |  |  |  |  |
Transaction price | $ 3,400 |  |  |  |  |
Ionis | Ionis Share Purchase Agreement | American Depositary Shares |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Purchase price per share | $ 31.11 |  |  |  |  |

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