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Significant agreements - Bayer Collaboration Agreement (Details)
$ in Thousands, £ in Millions
 3 Months Ended 9 Months Ended
May 04, 2023
USD ($)
item
Sep. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Sep. 30, 2024
USD ($)
Sep. 30, 2023
USD ($)
Dec. 31, 2023
USD ($)
May 04, 2023
GBP (£)
item
Dec. 31, 2022
USD ($)
Significant agreements.                
Revenue from collaborative arrangement   $ 2,676 $ 5,352 $ 31,567 $ 21,645      
Deferred revenue   109,191   109,191   $ 135,194   $ 61,873
Bayer Collaboration Agreement                
Significant agreements.                
Number of collaboration targets | item 2           2  
Upfront cash payment $ 45,000              
Milestone payments receivable | £             £ 583.5  
Period to terminate agreement upon written notice for uncured material breach 90 days              
Number of business days to terminate agreement upon non payment by Bayer 20 days              
Transaction price $ 47,500              
Estimated amount payable to CROs $ 2,500              
Expected period for satisfaction of performance obligations 4 years              
Material rights exercise period 7 years              
Revenue from collaborative arrangement   834 $ 434 2,496 $ 434      
Deferred revenue   $ 43,515   $ 43,515   $ 43,618   $ 0
Bayer Collaboration Agreement | Minimum                
Significant agreements.                
Number of candidate compounds into further development | item 1           1  
Threshold period to terminate agreement upon written notice by Bayer 60 days              
Bayer Collaboration Agreement | Maximum                
Significant agreements.                
Number of collaboration targets | item 3           3  
Milestone payments receivable | £             £ 194.5  
Threshold period to terminate agreement upon written notice by Bayer 90 days              
Bayer Collaboration Agreement | Development and regulatory milestones | Maximum                
Significant agreements.                
Milestone payments receivable | £             178.3  
Bayer Collaboration Agreement | Across all three potential target programs                
Significant agreements.                
Milestone payments receivable | £             £ 534.9