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Property and equipment, net (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Property and equipment, net |  |  |
Finance lease right-of-use assets | $ 1,033 |  |
Property and equipment, gross | 28,465 | $ 27,908 |
Less: Accumulated depreciation and amortization | (18,949) | (13,393) |
Property and equipment, net | 9,516 | 14,515 |
Depreciation and amortization expense | 7,200 | 6,500 | $ 3,700
Amortization expense of property and equipment under finance leases | 53 | 0 | $ 0
Laboratory equipment |  |  |
Property and equipment, net |  |  |
Property and equipment | 14,658 | 15,554 |
Leasehold improvements |  |  |
Property and equipment, net |  |  |
Property and equipment | 10,903 | 11,000 |
Computer equipment and software |  |  |
Property and equipment, net |  |  |
Property and equipment | 581 | 532 |
Furniture and office equipment |  |  |
Property and equipment, net |  |  |
Property and equipment | $ 1,290 | $ 822 |

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- Definition The current period expense charged against earnings on long-lived, physical assets not used in production, and which are not intended for resale, to allocate or recognize the cost of such assets over their useful lives; or to record the reduction in book value of an intangible asset over the benefit period of such asset; or to reflect consumption during the period of an asset that is not used in production. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (b) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482740/230-10-45-28 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482099/360-10-50-1 + Details
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- Definition Amount of amortization expense attributable to right-of-use asset from finance lease. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 55 -Paragraph 53 -Publisher FASB -URI https://asc.fasb.org/1943274/2147479589/842-20-55-53 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 45 -Paragraph 4 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147479041/842-20-45-4 Reference 3: http://www.xbrl.org/2003/role/disclosureRef -Topic 842 -SubTopic 20 -Name Accounting Standards Codification -Section 50 -Paragraph 4 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147478964/842-20-50-4 + Details
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