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Significant agreements - Bayer Collaboration Agreement (Details) $ in Thousands, £ in Millions |  | 12 Months Ended |
--- | --- | --- | ---
May 04, 2023 USD ($) item | Dec. 31, 2024 USD ($) | Dec. 31, 2023 USD ($) | Dec. 31, 2022 USD ($) | May 04, 2023 GBP (£) item
Significant agreements. |  |  |  |  |
Revenue from collaborative arrangement |  | $ 35,275 | $ 26,976 | $ 14,463 |
Deferred revenue |  | 101,658 | 135,194 | 61,873 |
Bayer Collaboration Agreement |  |  |  |  |
Significant agreements. |  |  |  |  |
Number of collaboration targets | item | 2 |  |  |  | 2
Upfront cash payment | $ 45,000 |  |  |  |
Milestone payments, receivable | £ |  |  |  |  | £ 583.5
Period to terminate agreement upon written notice for uncured material breach | 90 days |  |  |  |
Number of business days to terminate agreement upon non payment by Bayer | 20 days |  |  |  |
Estimated amount payable to CROs | $ 2,500 |  |  |  |
Transaction price | $ 47,500 |  |  |  |
Expected period for satisfaction of performance obligations | 4 years |  |  |  |
Material rights exercise period | 7 years |  |  |  |
Revenue from collaborative arrangement |  | 3,393 | 1,160 | $ 0 |
Deferred revenue |  | $ 39,960 | $ 43,618 |  |
Bayer Collaboration Agreement | Minimum |  |  |  |  |
Significant agreements. |  |  |  |  |
Number of candidate compounds into further development | item | 1 |  |  |  | 1
Threshold period to terminate agreement upon written notice by Bayer | 60 days |  |  |  |
Bayer Collaboration Agreement | Maximum |  |  |  |  |
Significant agreements. |  |  |  |  |
Number of collaboration targets | item | 3 |  |  |  | 3
Milestone payments receivable | £ |  |  |  |  | £ 194.5
Threshold period to terminate agreement upon written notice by Bayer | 90 days |  |  |  |
Bayer Collaboration Agreement | Development and regulatory milestones | Maximum |  |  |  |  |
Significant agreements. |  |  |  |  |
Milestone payments receivable | £ |  |  |  |  | 178.3
Bayer Collaboration Agreement | Across all three potential target programs |  |  |  |  |
Significant agreements. |  |  |  |  |
Milestone payments receivable | £ |  |  |  |  | £ 534.9

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