XML 42 R4.htm IDEA: XBRL DOCUMENT v3.25.0.1
Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Consolidated Statements of Operations and Comprehensive Loss      
Collaboration revenue $ 35,275 $ 26,976 $ 14,463
Operating expenses:      
Research and development 172,966 156,496 81,609
General and administrative 72,181 60,426 49,507
Total operating expenses 245,147 216,922 131,116
Loss from operations (209,872) (189,946) (116,653)
Other income (expense):      
Interest and other income 34,284 14,002 5,756
Interest expense (1,730) (3,263) (3,344)
Loss on extinguishment of debt (954)    
Gain on extinguishment of research and development funding liability 4,476    
Total other income, net 36,076 10,739 2,412
Net loss before income tax provision (173,796) (179,207) (114,241)
(Benefit from) provision for income taxes (4,765) 1,457 (1,524)
Net loss $ (169,031) $ (180,664) $ (112,717)
Net loss per share, basic $ (2.9) $ (5.08) $ (3.8)
Net loss per share, diluted $ (2.9) $ (5.08) $ (3.8)
Weighted average ordinary shares outstanding, basic 58,207,593 35,592,362 29,660,659
Weighted average ordinary shares outstanding, diluted 58,207,593 35,592,362 29,660,659
Comprehensives loss:      
Net loss $ (169,031) $ (180,664) $ (112,717)
Other comprehensive income (loss):      
Foreign currency translation adjustment 1,423 (1,691) 3,775
Total comprehensive loss $ (167,608) $ (182,355) $ (108,942)