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Consolidated Statements of Shareholders' Equity - USD ($)
$ in Thousands
Ordinary Shares
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Total
Beginning balance at Dec. 31, 2021 $ 384 $ 567,637 $ (3,388) $ (218,379) $ 346,254
Beginning balance (in shares) at Dec. 31, 2021 29,579,364        
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options $ 1 988     989
Issuance of ADSs upon exercise of share options (in shares) 78,074        
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses $ 2 5,701     5,703
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses (in shares) 181,455        
Issuance of ADSs upon settlement of restricted share units (in shares) 35,000        
Share-based compensation expense   26,779     26,779
Foreign currency translation adjustment     3,775   3,775
Net Income (Loss)       (112,717) (112,717)
Ending balance at Dec. 31, 2022 $ 387 601,105 387 (331,096) 270,783
Ending balance (in shares) at Dec. 31, 2022 29,873,893        
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options   681     681
Issuance of ADSs upon exercise of share options (in shares) 54,023        
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses $ 162 249,183     249,345
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses (in shares) 12,384,706        
Issuance of ADSs upon settlement of restricted share units $ 1       1
Issuance of ADSs upon settlement of restricted share units (in shares) 119,144        
Share-based compensation expense   32,477     32,477
Foreign currency translation adjustment     (1,691)   (1,691)
Net Income (Loss)       (180,664) (180,664)
Ending balance at Dec. 31, 2023 $ 550 883,446 (1,304) (511,760) $ 370,932
Ending balance (in shares) at Dec. 31, 2023 42,431,766       42,431,766
Increase (decrease) in shareholders' equity (deficit)          
Issuance of ADSs upon exercise of share options $ 8 7,519     $ 7,527
Issuance of ADSs upon exercise of share options (in shares) 554,596        
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses $ 331 543,796     544,127
Issuance of ADSs and non-voting ordinary shares, net of commissions and offering expenses (in shares) 25,933,706        
Issuance of ADSs upon settlement of restricted share units $ 1       1
Issuance of ADSs upon settlement of restricted share units (in shares) 141,350        
Share-based compensation expense   38,081     38,081
Foreign currency translation adjustment     1,423   1,423
Net Income (Loss)       (169,031) (169,031)
Ending balance at Dec. 31, 2024 $ 890 $ 1,472,842 $ 119 $ (680,791) $ 793,060
Ending balance (in shares) at Dec. 31, 2024 69,061,418       69,061,418