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Significant agreements - Cancer Research UK (Details) $ in Thousands			12 Months Ended
	Dec. 04, 2024 GBP (£)	Dec. 13, 2016 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2023 USD ($)
Research and development arrangement obligation to repay other parties
Contingent future milestones payments under research and development arrangement		$ 50,900
Gain on extinguishment of research and development funding liability			$ 4,476
BT1718
Research and development arrangement obligation to repay other parties
Liability from research and development				$ 4,300
Research and Development Arrangement, Upfront Cash Payment | £	£ 50,000
Gain on extinguishment of research and development funding liability			$ 4,500
BT1718 | Minimum
Research and development arrangement obligation to repay other parties
Tiered royalties (percentage)		70.00%
BT1718 | Maximum
Research and development arrangement obligation to repay other parties
Tiered royalties (percentage)		90.00%

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- Definition

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Percentage of tiered royalty on net revenue.

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- Definition

Represents the liability recorded for research and development arrangement.

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- Definition

Represents payments due upon achievement of milestones under a Research and Development arrangement.

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Amount of upfront cash payment made on research and development arrangement.

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