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Income taxes - Reconciliation of benefit for income taxes (Details)
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Income taxes      
(Benefit from) provision for income taxes at statutory rate 25.00% 23.50% 19.00%
Increases (decreases) resulting from:      
Tax credits 3.70% 0.60% 0.40%
Change in valuation allowance (11.20%) (14.80%) (16.80%)
Net losses surrendered for research credit (14.20%) (11.10%) (6.50%)
Impact of statutory rate change   2.70% 11.30%
Impact of foreign exchange rates (1.00%) (0.10%) (9.90%)
Other 0.40% (1.60%) 3.80%
Effective income tax rate 2.70% (0.80%) 1.30%