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Net Income (Loss) Per Ordinary Share | 9 Months Ended
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Sep. 30, 2025
Earnings Per Share [Abstract] |
Net Income (Loss) Per Ordinary Share | Net Loss Per Ordinary Share Net loss per ordinary share was determined as follows (in thousands, except per share amounts):
| Three Months Ended September 30, |  | Nine Months Ended September 30,
| 2025 |  | 2024 |  | 2025 |  | 2024
Numerator: |  |  |  |  |  |  |
Net loss | $ | (36,541) |  |  | $ | (59,001) |  |  | $ | (222,503) |  |  | $ | (64,354) |
Denominator: |  |  |  |  |  |  |
Weighted-average ordinary shares outstanding used in per share calculations | 53,830 |  |  | 53,790 |  |  | 53,828 |  |  | 53,757 |
Net loss per share: |  |  |  |  |  |  |
Basic and diluted net loss per ordinary share | $ | (0.68) |  |  | $ | (1.10) |  |  | $ | (4.13) |  |  | $ | (1.20) |
Potentially issuable ordinary shares were not used in computing diluted net loss per ordinary share as their effect would be anti-dilutive due to the loss recorded during the three and nine months ended September 30, 2025 and 2024, and therefore diluted net loss per share is equal to basic net loss per share. The equivalent ordinary shares not included in diluted net income (loss) per share because their effect would be anti-dilutive are as follows (in thousands):
| Three Months Ended September 30, |  | Nine Months Ended September 30,
| 2025 |  | 2024 |  | 2025 |  | 2024
Stock options to purchase ordinary shares | 11,627 |  |  | 11,297 |  |  | 11,627 |  |  | 11,297 |
Restricted Stock Units (RSU) | 1,133 |  |  | 24 |  |  | 1,133 |  |  | 24 |
Total | 12,760 |  |  | 11,321 |  |  | 12,760 |  |  | 11,321 |

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