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Share-Based Compensation - Summary of Share-Based Compensation Expense (Details) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 | Sep. 30, 2024 | Sep. 30, 2025 | Sep. 30, 2024
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Share-based compensation expense | $ 7,199 | $ 11,020 | $ 30,566 | $ 35,444
Research and development |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Share-based compensation expense | 2,471 | 5,128 | 11,990 | 16,217
General and administrative |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Share-based compensation expense | 4,728 | 5,892 | 16,495 | 19,227
Restructuring costs |  |  |  |
Share-based Compensation Arrangement by Share-based Payment Award [Line Items] |  |  |  |
Share-based compensation expense | $ 0 | $ 0 | $ 2,081 | $ 0

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