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Net Income (Loss) Per Ordinary Share (Tables) | 9 Months Ended
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Sep. 30, 2025
Earnings Per Share [Abstract] |
Calculation of Basic and Diluted Net Income (Loss) Per Ordinary Share | Net loss per ordinary share was determined as follows (in thousands, except per share amounts):
| Three Months Ended September 30, |  | Nine Months Ended September 30,
| 2025 |  | 2024 |  | 2025 |  | 2024
Numerator: |  |  |  |  |  |  |
Net loss | $ | (36,541) |  |  | $ | (59,001) |  |  | $ | (222,503) |  |  | $ | (64,354) |
Denominator: |  |  |  |  |  |  |
Weighted-average ordinary shares outstanding used in per share calculations | 53,830 |  |  | 53,790 |  |  | 53,828 |  |  | 53,757 |
Net loss per share: |  |  |  |  |  |  |
Basic and diluted net loss per ordinary share | $ | (0.68) |  |  | $ | (1.10) |  |  | $ | (4.13) |  |  | $ | (1.20) |
Ordinary Shares Equivalent Not Included in Diluted Net Income (Loss) Per Ordinary Share | The equivalent ordinary shares not included in diluted net income (loss) per share because their effect would be anti-dilutive are as follows (in thousands):
| Three Months Ended September 30, |  | Nine Months Ended September 30,
| 2025 |  | 2024 |  | 2025 |  | 2024
Stock options to purchase ordinary shares | 11,627 |  |  | 11,297 |  |  | 11,627 |  |  | 11,297 |
Restricted Stock Units (RSU) | 1,133 |  |  | 24 |  |  | 1,133 |  |  | 24 |
Total | 12,760 |  |  | 11,321 |  |  | 12,760 |  |  | 11,321 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482662/260-10-50-1 + Details
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- Definition Tabular disclosure of an entity's basic and diluted earnings per share calculations, including a reconciliation of numerators and denominators of the basic and diluted per-share computations for income from continuing operations. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Topic 260 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482662/260-10-50-1 + Details
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