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Share-based Compensation - Share-based Compensation Plan - Option Activity (Details) - USD ($)
$ / shares in Units, $ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2025
Dec. 31, 2024
Share-Based Payment, Options, Outstanding [Roll Forward]    
Options, outstanding beginning balance (in shares) 11,107,373  
Options, granted (in shares) 2,086,686  
Options, exercised (in shares) 0  
Options, forfeited (in shares) (1,331,514)  
Options, expired (in shares) (235,332)  
Options, outstanding ending balance (in shares) 11,627,213 11,107,373
Options, vested and expected to vest ending balance (in shares) 11,259,635  
Options, Exercisable (in shares) 8,902,882  
Share-Based Payment, Options, Outstanding, Weighted Average Exercise Price [Abstract]    
Weighted average exercise price, outstanding beginning balance (in dollars per share) $ 28.70  
Weighted average exercise price, granted (in dollars per share) 14.26  
Weighted average exercise price, exercised (in dollars per share) 0  
Weighted average exercise price, forfeited (in dollars per share) 29.02  
Weighted average exercise price, expired (in dollars per share) 27.70  
Weighted average exercise price, outstanding ending balance (in dollars per share) 26.09 $ 28.70
Weighted average exercise price, vested and expected to vest, ending balance (in dollars per share) 26.23  
Weighted Average Exercise Price, Exercisable (in dollars per shares) $ 26.75  
Share-Based Payment, Options, Additional Disclosures [Abstract]    
Weighted average remaining contractual term, outstanding (in years) 4 years 9 months 6 years 1 month 28 days
Weighted average remaining contractual term, vested and expected to vest (in years) 4 years 7 months 13 days  
Weighted Average Remaining Contractual Term, exercisable (in years) 3 years 7 months 6 days  
Aggregate intrinsic value, outstanding $ 505 $ 3,401
Aggregate intrinsic value, vested and expected to vest, ending balance 472  
Aggregate intrinsic value, exercisable $ 37