<SEC-DOCUMENT>0001193125-22-183827-index.html : 20220628
<SEC-HEADER>0001193125-22-183827.hdr.sgml : 20220628
<ACCEPTANCE-DATETIME>20220628145859
ACCESSION NUMBER:		0001193125-22-183827
CONFORMED SUBMISSION TYPE:	11-K
PUBLIC DOCUMENT COUNT:		3
CONFORMED PERIOD OF REPORT:	20211231
FILED AS OF DATE:		20220628
DATE AS OF CHANGE:		20220628

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CASS INFORMATION SYSTEMS INC
		CENTRAL INDEX KEY:			0000708781
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-BUSINESS SERVICES, NEC [7389]
		IRS NUMBER:				431265338
		STATE OF INCORPORATION:			MO
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		11-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-20827
		FILM NUMBER:		221049301

	BUSINESS ADDRESS:	
		STREET 1:		12444 POWERSCOURT DRIVE
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63131
		BUSINESS PHONE:		314-506-5500

	MAIL ADDRESS:	
		STREET 1:		12444 POWERSCOURT DRIVE
		CITY:			ST. LOUIS
		STATE:			MO
		ZIP:			63131

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CASS COMMERCIAL CORP
		DATE OF NAME CHANGE:	19950518
</SEC-HEADER>
<DOCUMENT>
<TYPE>11-K
<SEQUENCE>1
<FILENAME>d366156d11k.htm
<DESCRIPTION>11-K
<TEXT>
Document 1 - file: d366156d11k.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>2
<FILENAME>d366156dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 2 - file: d366156dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>g366156g0628005516536.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: g366156g0628005516536.jpg

</DOCUMENT>
</SEC-DOCUMENT>