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Note G - Stock-based Compensation (Tables)
6 Months Ended
Jun. 30, 2016
Notes Tables  
Schedule of Employee Service Share-based Compensation, Allocation of Recognized Period Costs [Table Text Block]
   
Three Months Ended
June 30,
   
Six Months Ended
June 30,
 
   
2016
   
2015
   
2016
   
2015
 
Research and development
  $ 268     $ 185     $ 455     $ 220  
General and administrative
    989       688       1,824       744  
    $ 1,257     $ 873     $ 2,279     $ 964