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Unaudited Condensed Statements of Operations - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Revenue
Operating expenses:        
Research and development 4,988 2,768 8,222 4,887
General and administrative 4,287 3,188 8,023 4,165
Total operating expenses 9,275 5,956 16,245 9,052
Loss from operations (9,275) (5,956) (16,245) (9,052)
Other income (expense):        
Loss on extinguishment of debt (4,740)
Interest expense related to amortization of debt issuance costs and discount (393) (477) (835) (954)
Interest expense on principal (1,475) (654) (2,625) (1,286)
Fair value adjustment 20,763 (22,661) 31,041 (24,423)
Interest and other income 144 5 246 6
Total other income (expense) 19,039 (23,787) 23,087 (26,657)
Income (loss) before income taxes 9,764 (29,743) 6,842 (35,709)
Income tax benefit (expense) 4 (8) (7)
Net income (loss) $ 9,768 $ (29,743) $ 6,834 $ (35,716)
Net income (loss) per share:        
Basic (in dollars per share) $ 0.59 $ (2.45) $ 0.41 $ (4.91)
Diluted loss per share of common stock (in dollars per share) $ (0.58) $ (2.45) $ (1.36) $ (4.91)
Weighted average common shares outstanding:        
Basic (in shares) 14,597,449 12,157,514 14,546,576 7,272,326
Diluted (in shares) 15,435,322 12,157,514 15,583,390 7,272,326