    <SEC-DOCUMENT>0001437749-23-006905-index.html : 20230316
    <SEC-HEADER>0001437749-23-006905.hdr.sgml : 20230316
    <ACCEPTANCE-DATETIME>20230316162343
    ACCESSION NUMBER:		0001437749-23-006905
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		5
    FILED AS OF DATE:		20230316
    DATE AS OF CHANGE:		20230316

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ZEVRA THERAPEUTICS, INC.
    		CENTRAL INDEX KEY:			0001434647
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				205894398
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-36913
    		FILM NUMBER:		23739143

    	BUSINESS ADDRESS:
    		STREET 1:		1180 CELEBRATION BOULEVARD, SUITE 103
    		CITY:			CELEBRATION
    		STATE:			FL
    		ZIP:			34747
    		BUSINESS PHONE:		(321) 939-3416

    	MAIL ADDRESS:
    		STREET 1:		1180 CELEBRATION BOULEVARD, SUITE 103
    		CITY:			CELEBRATION
    		STATE:			FL
    		ZIP:			34747

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	KEMPHARM, INC
    		DATE OF NAME CHANGE:	20130530

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	KEMPHARM INC
    		DATE OF NAME CHANGE:	20080507
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEFA14A
    <SEQUENCE>1
    <FILENAME>zvra20230315_defa14a.htm
    <DESCRIPTION>FORM DEFA14A
    <TEXT>
    Document 1 - file: zvra20230315_defa14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>page1.jpg
    <TEXT>
    Document 2 - file: page1.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>page2.jpg
    <TEXT>
    Document 3 - file: page2.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>page3.jpg
    <TEXT>
    Document 4 - file: page3.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>5
    <FILENAME>page4.jpg
    <TEXT>
    Document 5 - file: page4.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>