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                                                                    EXHIBIT 23.2

                 NOTICE REGARDING CONSENT OF ARTHUR ANDERSEN LLP

      The financial statements of Lexicon Genetics Incorporated as of December
31, 2001 and 2000, and for years then ended, included in this annual report on
Form 10-K have been audited by Arthur Andersen LLP, independent public
accountants. Arthur Andersen LLP has since ceased operations.

      This annual report on Form 10-K is incorporated by reference into
Lexicon's registration statements on Form S-8 (Registration Nos. 333-41532 and
333-66380) and on Form S-3 (Registration Nos. 333-67294 and 333-101549) and the
prospectuses relating thereto. Arthur Andersen LLP has not reissued its report
on Lexicon's financial statements as of December 31, 2001 and 2000, and for the
years then ended, in connection with this annual report on Form 10-K. In
addition, after reasonable efforts, and in reliance upon Rule 437a under the
Securities Act of 1933, we have not been able to obtain the consent of Arthur
Andersen LLP with respect to the incorporation by reference of such report in
the registration statements and prospectuses referenced above. Because Arthur
Andersen LLP has not consented to the inclusion of such report in the
registration statements and prospectuses referenced above, purchasers under such
prospectuses will not be able to recover against Arthur Andersen LLP under
Section 11(a) of the Securities Act for any untrue statements of a material fact
contained in the financial statements audited by Arthur Andersen LLP or any
omissions to state a material fact required to be stated therein.

