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Consolidated Statements of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified | 12 Months Ended
--- | ---
Dec. 31, 2011 | Dec. 31, 2010 | Dec. 31, 2009
Revenues: |  |  |
Collaborative research | $ 1,632 | $ 4,191 | $ 9,334
Subscription and license fees | 217 | 717 | 1,366
Total revenues | 1,849 | 4,908 | 10,700
Operating expenses: |  |  |
Research and development, including stock-based compensation of $3,249, $3,170 and $3,022, respectively | 91,828 | 78,520 | 81,238
Increase in fair value of Symphony Icon, Inc. purchase liability | 6,766 | 2,710 | 0
General and administrative, including stock-based compensation of $2,458, $2,308 and $2,252, respectively | 17,350 | 19,396 | 19,418
Total operating expenses | 115,944 | 100,626 | 100,656
Loss from operations | (114,095) | (95,718) | (89,956)
Gain on investments, net | 0 | 141 | 1,173
Interest income | 255 | 519 | 880
Interest expense | (2,528) | (2,719) | (2,966)
Other income (expense), net | 153 | (4,024) | (2,550)
Consolidated net loss before taxes | (116,215) | (101,801) | (93,419)
Income tax benefit | 0 | 26 | 102
Consolidated net loss | (116,215) | (101,775) | (93,317)
Less: net loss attributable to Symphony Icon, Inc. | 0 | 0 | 10,537
Net loss attributable to Lexicon Pharmaceuticals, Inc. | $ (116,215) | $ (101,775) | $ (82,780)
Net loss attributable to Lexicon Pharmaceuticals, Inc. per common share, basic and diluted | $ (0.34) | $ (0.34) | $ (0.57)
Shares used in computing net loss attributable to Lexicon Pharmaceuticals, Inc. per common share, basic and diluted | 340,761 | 302,844 | 145,465

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- Definition Aggregate revenue recognized during the period (derived from goods sold, services rendered, insurance premiums, or other activities that constitute an entity's earning process). For financial services companies, also includes investment and interest income, and sales and trading gains. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Article 5 -Section 03 -Paragraph 1 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.1) -URI http://asc.fasb.org/extlink&oid=6880815&loc=d3e20235-122688 + Details
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