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Consolidated Statements of Comprehensive Loss (Unaudited) (USD $)
In Thousands, except Per Share data, unless otherwise specified
3 Months Ended 9 Months Ended
Sep. 30, 2012
Sep. 30, 2011
Sep. 30, 2012
Sep. 30, 2011
Revenues:        
Collaborative research $ 214 $ 335 $ 565 $ 1,312
Subscription and license fees 158 20 306 194
Total revenues 372 355 871 1,506
Operating expenses:        
Research and development, including stock-based compensation of $923, $823, $2,875 and $2,480, respectively 19,192 19,655 61,584 63,721
Increase in fair value of Symphony Icon, Inc. purchase liability 5,844 2,336 10,087 5,198
General and administrative, including stock-based compensation of $669, $609, $2,030 and $1,874, respectively 4,396 4,055 13,123 13,340
Total operating expenses 29,432 26,046 84,794 82,259
Loss from operations (29,060) (25,691) (83,923) (80,753)
Interest income 44 60 158 215
Interest expense (527) (560) (1,594) (1,977)
Other income, net 4 88 21 145
Consolidated net loss (29,539) (26,103) (85,338) (82,370)
Consolidated net loss per common share, basic and diluted $ (0.06) $ (0.08) $ (0.18) $ (0.24)
Shares used in computing consolidated net loss per common share, basic and diluted 490,049 337,678 483,693 337,625
Unrealized gain (loss) on investments 41 (37) 0 29
Comprehensive loss $ (29,498) $ (26,140) $ (85,338) $ (82,341)