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Summary of Significant Accounting Policies Concentration of Credit Risk (Details) | 12 Months Ended
--- | ---
Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2010
Concentration Risk [Line Items] |  |  |
Disclosure on Geographic Areas, Revenue from External Customers Attributed to Entity's Country of Domicile, Percent | 100.00% | 100.00% | 94.00%
Disclosure on Geographic Areas, Revenue from External Customers Attributed to Europe, Percent |  |  | 6.00%

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- Definition Revenues from external customers attributed to the entity's country of domicile as a percentage of total revenue. + References No definition available. + Details
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Namespace Prefix: | lxrx_
Data Type: | num:percentItemType
Balance Type: | na
Period Type: | duration

X
- Definition Revenues from external customers attributed to Europe as a percentage of total revenue. + References No definition available. + Details
Name: | lxrx_DisclosureOnGeographicAreasRevenueFromExternalCustomersAttributedToEuropePercent
Namespace Prefix: | lxrx_
Data Type: | num:percentItemType
Balance Type: | na
Period Type: | duration

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- Details
Name: | us-gaap_ConcentrationRiskLineItems
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration