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Consolidated Statements of Cash Flows (Unaudited) (USD $) In Thousands, unless otherwise specified | 9 Months Ended
--- | ---
Sep. 30, 2014 | Sep. 30, 2013
Cash flows from operating activities: |  |
Consolidated net loss | $ (97,361) | $ (86,712)
Adjustments to reconcile consolidated net loss to net cash used in operating activities: |  |
Depreciation | 1,724 | 2,194
Impairment of fixed assets | 13,344 | 0
Increase in fair value of Symphony Icon, Inc. purchase liability | 518 | 3,079
Stock-based compensation | 5,584 | 5,728
Gain on disposal of property and equipment | (811) | 0
Changes in operating assets and liabilities: |  |
Decrease in accounts receivable | 625 | 483
Increase in prepaid expenses and other current assets | (1,301) | (908)
Decrease in other assets | 63 | 62
Increase in accounts payable and other liabilities | 6,587 | 6,684
Increase (decrease) in deferred revenue | (136) | 52
Net cash used in operating activities | (71,164) | (69,338)
Cash flows from investing activities: |  |
Purchases of property and equipment | (46) | (1,506)
Proceeds from disposal of property and equipment | 1,808 | 108
Purchases of investments | (20,651) | (80,954)
Maturities of investments | 81,186 | 142,125
Net cash provided by investing activities | 62,297 | 59,773
Cash flows from financing activities: |  |
Proceeds from issuance of common stock | 325 | 874
Repurchase of common stock | (887) | (873)
Repayment of debt borrowings | (1,268) | (1,167)
Other financing activities | (27) | (111)
Net cash used in financing activities | (1,857) | (1,277)
Net decrease in cash and cash equivalents | (10,724) | (10,842)
Cash and cash equivalents at beginning of period | 37,499 | 30,423
Cash and cash equivalents at end of period | 26,775 | 19,581
Supplemental disclosure of cash flow information: |  |
Cash paid for interest | 1,355 | 1,437
Supplemental disclosure of non-cash investing and financing activities: |  |
Unrealized gain on investments | $ 0 | $ 15

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- Definition This item represents the change in fair value of the Symphony Icon, Inc. purchase liability. In connection with the acquisition of Symphony Icon, Lexicon made an initial estimate of the fair value of the liability for the associated based and contingent payments. Changes in this liability, based on the development of the programs and the time until such payments are expected to be made, are recorded in Lexicon's consolidated statements of operations. + References No definition available. + Details
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- Definition Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash -URI http://asc.fasb.org/extlink&oid=6506951 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Glossary Cash Equivalents -URI http://asc.fasb.org/extlink&oid=6507016 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher SEC -Name Regulation S-X (SX) -Number 210 -Section 02 -Paragraph 1 -Article 5 Reference 4: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.1) -URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682 Reference 5: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section 45 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=28358313&loc=d3e6676-107765 Reference 6: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 4 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3044-108585 + Details
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- Definition Amount of increase (decrease) in cash and cash equivalents. Cash and cash equivalents are the amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Includes effect from exchange rate changes. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 24 -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3521-108585 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 830 -SubTopic 230 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6450594&loc=d3e33268-110906 + Details
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- Definition The net change in the difference between the fair value and the carrying value, or in the comparative fair values, of investments, not including unrealized gains or losses on securities separately or otherwise categorized as trading, available-for-sale, or held-to-maturity, held at each balance sheet date and included in earnings for the period. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=31042434&loc=d3e3602-108585 + Details
Name: | us-gaap_UnrealizedGainLossOnInvestments
Namespace Prefix: | us-gaap_
Data Type: | xbrli:monetaryItemType
Balance Type: | credit
Period Type: | duration