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Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) shares in Thousands, $ in Thousands | Total | Common Stock | Additional Paid-In Capital | Accumulated Deficit | Accumulated Other Comprehensive Gain (Loss) | Treasury Stock
--- | --- | --- | --- | --- | --- | ---
Balance, shares at Dec. 31, 2016 |  | 104,582 |  |  |  |
Balance, value at Dec. 31, 2016 | $ 157,401 | $ 105 | $ 1,411,222 | $ (1,250,363) | $ (195) | $ (3,368)
Cumulative effect from accounting change | 0 |  | 1,991 | (1,991) | 0 | 0
Issuance of common stock to designees of Symphony Icon Holdings LLC, shares |  | 660 |  |  |  |
Issuance of common stock to designees of Symphony Icon Holdings LLC, value | 10,499 | $ 0 | 10,499 | 0 | 0 | 0
Stock-based compensation | 7,214 | $ 0 | 7,214 | 0 | 0 | 0
Issuance of common stock under Equity Incentive Plans, shares |  | 468 |  |  |  |
Issuance of common stock under Equity Incentive Plans, value | 5,481 | $ 1 | 5,480 | 0 | 0 | 0
Stock Issued During Period, Value, Treasury Stock Reissued | 0 |  | (3,143) | 0 | 0 | (3,143)
Repurchase of common stock | (1,679) | 0 | 0 | 0 | 0 | (1,679)
Net loss | (100,672) | 0 | 0 | (100,672) | 0 | 0
Unrealized gain on investments | 132 | $ 0 | 0 | 0 | 132 | 0
Balance, shares at Sep. 30, 2017 |  | 105,710 |  |  |  |
Balance, value at Sep. 30, 2017 | 78,376 | $ 106 | 1,433,263 | (1,353,026) | (63) | (1,904)
Balance, shares at Dec. 31, 2017 |  | 105,711 |  |  |  |
Balance, value at Dec. 31, 2017 | 52,102 | $ 106 | 1,435,526 | (1,381,404) | (222) | (1,904)
Cumulative effect from accounting change | 14,212 | 0 | 0 | 14,212 | 0 | 0
Issuance of common stock to designees of Symphony Icon Holdings LLC, value | 0 |  |  |  |  |
Stock-based compensation | 8,849 | $ 0 | 8,849 | 0 | 0 | 0
Issuance of common stock under Equity Incentive Plans, shares |  | 423 |  |  |  |
Issuance of common stock under Equity Incentive Plans, value | 550 | $ 0 | 550 | 0 | 0 | 0
Repurchase of common stock | (972) | 0 | 0 | 0 | 0 | (972)
Net loss | (104,293) | 0 | 0 | (104,293) | 0 | 0
Unrealized gain on investments | 151 | $ 0 | 0 | 0 | 151 | 0
Balance, shares at Sep. 30, 2018 |  | 106,134 |  |  |  |
Balance, value at Sep. 30, 2018 | $ (29,401) | $ 106 | $ 1,444,925 | $ (1,471,485) | $ (71) | $ (2,876)

X
- Definition On July 30, 2010, Lexicon entered into an Amended and Restated Purchase Option Agreement with Symphony Icon and Holdings and simultaneously exercised the Purchase Option, thereby reacquiring the Programs. Pursuant to the amended terms of the Purchase Option, Lexicon paid Holdings $10 million and issued 13,237,591 shares of common stock to designees of Holdings on July 30, 2012 in satisfaction of an additional $35 million base payment obligation. Lexicon also agreed to make up to $45 million in additional payments, which will consist of 50% of any consideration Lexicon receives pursuant to any licensing transaction under which Lexicon grants a third party rights to commercialize LX1032, LX1033 or other pharmaceutical compositions modulating the same target as those drug candidates. This represents the shares issued to designees of Holdings during the period. + References No definition available. + Details
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- Definition On July 30, 2010, Lexicon entered into an Amended and Restated Purchase Option Agreement with Symphony Icon and Holdings and simultaneously exercised the Purchase Option, thereby reacquiring the Programs. Pursuant to the amended terms of the Purchase Option, Lexicon paid Holdings $10 million and issued 13,237,591 shares of common stock to designees of Holdings on July 30, 2012 in satisfaction of an additional $35 million base payment obligation. Lexicon also agreed to make up to $45 million in additional payments, which will consist of 50% of any consideration Lexicon receives pursuant to any licensing transaction under which Lexicon grants a third party rights to commercialize LX1032, LX1033 or other pharmaceutical compositions modulating the same target as those drug candidates. This represents the shares issued to designees of Holdings during the period. + References No definition available. + Details
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