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Statements of Comprehensive Loss Parentheticals (Parentheticals) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Stock-based compensation expense associated with research and development expense	$ 6,010	$ 4,905	$ 3,938
Stock-based compensation expense associated with general and administrative expense	$ 5,686	$ 4,567	$ 3,514

X

- Definition

Stock-based compensation expense associated with general and administrative expense.

+ References

No definition available.

+ Details

Name:	lxrx_StockBasedCompensationExpenseAssociatedWithGeneralAndAdministrativeExpense
Namespace Prefix:	lxrx_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

X

- Definition

Stock-based compensation expense included in research and development expense.

+ References

No definition available.

+ Details

Name:	lxrx_StockBasedCompensationExpenseAssociatedWithResearchAndDevelopmentExpense
Namespace Prefix:	lxrx_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration