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Consolidated Statements of Stockholders' Equity - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock
Additional Paid-In Capital
Accumulated Deficit
Accumulated Other Comprehensive Gain (Loss)
Treasury Stock
Balance, shares at Dec. 31, 2015   103,860        
Balance, value at Dec. 31, 2015 $ 285,972 $ 104 $ 1,397,646 $ (1,108,812) $ (219) $ (2,747)
Stock-based compensation 7,452 $ 0 7,452 0 0 0
Issuance of common stock to designees of Symphony Icon Holdings LLC, value 0          
Issuance of common stock under Equity Incentive Plans, shares   722        
Issuance of common stock under Equity Incentive Plans, value 6,125 $ 1 6,124 0 0 0
Repurchase of common stock (621) 0 0 0 0 621
Net loss (131,445) 0 0 (131,445) 0 0
Unrealized gain (loss) on investments 24 $ 0 0 0 24 0
Balance, shares at Dec. 31, 2016   104,582        
Balance, value at Dec. 31, 2016 167,507 $ 105 1,411,222 (1,240,257) (195) (3,368)
New Accounting Pronouncement or Change in Accounting Principle, Effect of Adoption, Quantification 0   1,991 (1,991) 0 0
Stock-based compensation 9,472 $ 0 9,472 0 0 0
Issuance of common stock to designees of Symphony Icon Holdings LLC, shares   660        
Issuance of common stock to designees of Symphony Icon Holdings LLC, value   $ 0        
Symphony Contingent Payment In Cash 10,499   10,499 0 0 0
Issuance of common stock under Equity Incentive Plans, shares   469        
Issuance of common stock under Equity Incentive Plans, value 5,486 $ 1 5,485 0 0 0
Issuance of Treasury Stock 0   (3,143) 0 0 (3,143)
Repurchase of common stock (1,679) 0 0 0 0 1,679
Net loss (122,993) 0 0 (122,993) 0 0
Unrealized gain (loss) on investments (27) $ 0 0 0 (27) 0
Balance, shares at Dec. 31, 2017   105,711        
Balance, value at Dec. 31, 2017 68,265 $ 106 1,435,526 (1,365,241) (222) (1,904)
New Accounting Pronouncement or Change in Accounting Principle, Effect of Adoption, Quantification 14,212   0 14,212 0 0
Stock-based compensation 11,696 $ 0 11,696 0 0 0
Issuance of common stock to designees of Symphony Icon Holdings LLC, value 0          
Issuance of common stock under Equity Incentive Plans, shares   451        
Issuance of common stock under Equity Incentive Plans, value 732 $ 0 732 0 0 0
Repurchase of common stock (972) 0 0 0 0 (972)
Net loss (120,548) 0 0 (120,548) 0 0
Unrealized gain (loss) on investments 210 $ 0 0 0 210 0
Balance, shares at Dec. 31, 2018   106,162        
Balance, value at Dec. 31, 2018 $ (26,405) $ 106 $ 1,447,954 $ (1,471,577) $ (12) $ (2,876)