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Commitments and Contingencies (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
	Sep. 30, 2020	Sep. 30, 2020	Sep. 30, 2019
Commitments and Contingencies Disclosure [Abstract]
Sanofi termination cash payment	$ 208,000	$ 26,000	$ 208,000
Other Commitments [Line Items]
Sanofi termination cash payment	$ 208,000	26,000	$ 208,000
Accounts Receivable [Member]
Commitments and Contingencies Disclosure [Abstract]
Sanofi termination cash payment		23,200
Other Commitments [Line Items]
Sanofi termination cash payment		$ 23,200

X

- Definition

lxrx_Sanofi termination cash payment - represents the cash payment from Sanofi to terminate the collaboration alliance

+ References

No definition available.

+ Details

Name:	lxrx_Lxrx_Sanofiterminationcashpayment
Namespace Prefix:	lxrx_
Data Type:	xbrli:monetaryItemType
Balance Type:	credit
Period Type:	duration

X

- References

No definition available.

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

Name:	us-gaap_OtherCommitmentsLineItems
Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
Balance Type:	na
Period Type:	duration

X

- Details

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Namespace Prefix:
Data Type:	na
Balance Type:
Period Type: