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v3.20.4

Consolidated Statements of Comprehensive Loss - USD ($) shares in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2020 | Dec. 31, 2019 | Dec. 31, 2018
Revenues: |  |  |
Net product revenue | $ 23,404,000 | $ 32,331,000 | $ 26,583,000
Collaborative agreements | 33,000 | 289,231,000 | 36,271,000
Royalties and other revenue | 558,000 | 511,000 | 355,000
Total revenues | 23,995,000 | 322,073,000 | 63,209,000
Operating expenses: |  |  |
Cost of sales (including finite-lived intangible asset amortization) | 1,929,000 | 3,231,000 | 2,491,000
Research and development, including stock-based compensation of $6,376, $7,096 and $6,010 respectively | 153,621,000 | 91,924,000 | 100,243,000
Selling, general and administrative, including stock-based compensation of $6,898, $7,122 and $5,686, respectively | 47,230,000 | 56,835,000 | 63,754,000
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill) | 1,600,000 | 0 | 0
Goodwill and Intangible Asset Impairment |  | 28,638,000 |
Total operating expenses | 204,380,000 | 180,628,000 | 166,488,000
Gain on sale of non-financial assets | 132,585,000 | 0 | 0
Income (loss) from operations | (47,800,000) | 141,445,000 | (103,279,000)
Recognition of gain or loss on extinguishment | 1,003,000 | 0 | 0
Interest expense | (14,544,000) | (20,676,000) | (20,777,000)
Interest and other income, net | 2,767,000 | 3,350,000 | 3,508,000
Net income (loss) before taxes | (58,574,000) | 124,119,000 | (120,548,000)
Income tax benefit | 0 | 6,014,000 | 0
Net income (loss) | (58,574,000) | 130,133,000 | (120,548,000)
Other comprehensive loss: |  |  |
Unrealized gain (loss) on investments | (90,000) | 96,000 | 210,000
Comprehensive loss | $ (58,664,000) | $ 130,229,000 | $ (120,338,000)
Earnings Per Share, Basic | $ (0.53) | $ 1.23 | $ (1.14)
Earnings Per Share, Diluted | $ (0.53) | $ 1.16 | $ (1.14)
Weighted Average Number of Shares Outstanding, Diluted | 110,841 | 116,747 | 105,830
Weighted Average Number of Shares Issued, Basic | 110,841 | 106,218 | 105,830

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