EX-99.22 2 d161164dex9922.htm EXHIBIT 22

Exhibit 22

EXHIBIT 22

FIFTH AMENDED AND RESTATED JOINT FILING AGREEMENT

This Fifth Amended and Restated Joint Filing Agreement (this “Agreement”) amends and restates the Fourth Amended and Restated Joint Filing Agreement, dated January 5, 2021, by and among Invus, L.P., Invus Advisors, L.L.C., Invus Public Equities, L.P., Invus Public Equities Advisors, LLC, Invus Partners, LLC, Ulys, L.L.C., Mr. Raymond Debbane, Artal Treasury Limited, Artal International S.C.A., Artal International Management S.A., Artal Group S.A., Westend S.A., Stichting Administratiekantoor Westend (the “Stichting”) and Mr. Pascal Minne.

We, the signatories of this statement on Schedule 13D to which this Agreement is attached, hereby agree that such statement is, and any amendments thereto filed by any of us will be, filed on behalf of each of us and on behalf of any affiliate of Invus, L.P. that executes a joinder hereto.

INVUS, L.P.
By: INVUS ADVISORS, L.L.C., its general partner
By:		/s/ Raymond Debbane
Name:		Raymond Debbane
Title:		President
INVUS PUBLIC EQUITIES, L.P.
By: INVUS PUBLIC EQUITIES ADVISORS, LLC, its general partner
By:		/s/ Raymond Debbane
Name:		Raymond Debbane
Title:		President
INVUS ADVISORS, L.L.C.
By:		/s/ Raymond Debbane
Name:		Raymond Debbane
Title:		President
INVUS PUBLIC EQUITIES ADVISORS, LLC
By:		/s/ Raymond Debbane
Name:		Raymond Debbane
Title:		President
ARTAL TREASURY LIMITED
By:		/s/ Keith Le Poidevin
Name:		Keith Le Poidevin
Title:		Director

ARTAL INTERNATIONAL S.C.A.
By: ARTAL INTERNATIONAL MANAGEMENT S.A., its managing partner
By:		/s/ Anne Goffard
Name:		Anne Goffard
Title:		Managing Director
ARTAL INTERNATIONAL MANAGEMENT S.A.
By:		/s/ Anne Goffard
Name:		Anne Goffard
Title:		Managing Director
ARTAL GROUP S.A.
By:		/s/ Anne Goffard
Name:		Anne Goffard
Title:		Authorized Person
WESTEND S.A.
By:		/s/ Anne Goffard
Name:		Anne Goffard
Title:		Managing Director
STICHTING ADMINISTRATIEKANTOOR WESTEND
By:		/s/ Amaury Wittouck
Name:		Amaury Wittouck
Title:		Sole Member of the Board
AMAURY WITTOUCK
By:		/s/ Amaury Wittouck

INVUSPARTNERS, LLC
By: ULYS, L.L.C., its managing member
By:		/s/ Raymond Debbane
Name:		Raymond Debbane
Title:		President
ULYS, L.L.C.
By:		/s/ Raymond Debbane
Name:		Raymond Debbane
Title:		President
RAYMOND DEBBANE
By:		/s/ Raymond Debbane
Dated:		January 21, 2021