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Summary of Significant Accounting Policies Segment Information and Signficant Customers (Details) - segment | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Accounting Policies [Abstract] |  |  |
Number of operating segments | 1 |  |
Entity Wide Revenue Sanofi Percentage |  |  | 89.00%
LXRX Diplomat customer concentration | 24.00% | 22.00% |
Biologics customer concentration | 76.00% | 65.00% |

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- Definition Percentage of revenue generated from Sanofi that accounts for 10 percent or more of an entity's revenues. + References No definition available. + Details
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- Definition LXRX Biologics customer concentration - represents percent of revenue that Biologics contributes to total revenues + References No definition available. + Details
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- Definition LXRX Diplomat customer concentration - represents the percent of revenue that Diplomat contributes to revenues + References No definition available. + Details
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Namespace Prefix: | lxrx_
Data Type: | dtr-types:percentItemType
Balance Type: | na
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- References No definition available. + Details
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- Definition Number of operating segments. An operating segment is a component of an enterprise: (a) that engages in business activities from which it may earn revenues and incur expenses (including revenues and expenses relating to transactions with other components of the same enterprise), (b) whose operating results are regularly reviewed by the enterprise's chief operating decision maker to make decisions about resources to be allocated to the segment and assess its performance, and (c) for which discrete financial information is available. An operating segment may engage in business activities for which it has yet to earn revenues, for example, start-up operations may be operating segments before earning revenues. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 18 -URI http://asc.fasb.org/extlink&oid=123359005&loc=d3e8672-108599 + Details
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