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Summary of Significant Accounting Policies Accrued Liabilities (Details) - USD ($) | Mar. 31, 2022 | Dec. 31, 2021 | Mar. 01, 2021
--- | --- | --- | ---
Accrued Liabilities [Line Items] |  |  |
Accrued research and development services current | $ 5,308,000 | $ 3,669,000 |
Accrued compensation and benefits current | 2,616,000 | 5,711,000 |
Operating Lease, Liability, Current | (940,000) | (1,089,000) |
Other Accrued Liabilities, Current | 720,000 | 2,503,000 |
Accrued Liabilities | $ 9,584,000 | $ 12,972,000 |
Lexicon incremental borrowing rate |  |  | 900.00%

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