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Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities:    
Net loss $ (23,476,000) $ (20,958,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 109,000 37,000
Stock-based compensation 2,772,000 2,851,000
Amortization of debt issuance costs 25,000 14,000
Changes in operating assets and liabilities:    
(Increase) decrease in accounts receivable (23,000) 294,000
(Increase) decrease in prepaid expenses and other current assets 273,000 1,095,000
Decrease in other assets 207,000 (74,000)
Decrease in accounts payable and other liabilities (3,308,000) (8,418,000)
Net cash provided by (used in) operating activities (23,421,000) (25,159,000)
Cash and Cash Equivalents, Period Increase (Decrease) (4,545,000) (28,611,000)
Cash and cash equivalents 59,520,000 97,652,000
Cash paid for interest 85,000 0
Initial recognition of right of use asset 0 1,700,000
Issuance of Stock and Warrants for Services or Claims 698  
Adjustments to Additional Paid in Capital, Warrant Issued 700,000 0
Stock Issued During Period, Value, Treasury Stock Reissued 6,321 0
Business Exit Costs 1,500 0
Issuance of common stock under Equity Incentive Plans, value (864,000)  
Cash flows from investing activities:    
Purchases of property and equipment (76,000) (38,000)
Purchases of investments (17,816,000) (21,686,000)
Maturities of investments 13,484,000 4,000,000
Net cash (used in) provided by investing activities (4,408,000) (17,724,000)
Cash flows from financing activities:    
Proceeds from issuance of common stock 0 16,947,000
Repurchase of common stock (864,000) (2,675,000)
Proceeds from debt borrowings, net of fees 24,148,000 0
Net cash used in financing activities 23,284,000 14,272,000
Net increase (decrease) in cash and cash equivalents (4,545,000) (28,611,000)
Cash and cash equivalents at beginning of period 64,065,000 126,263,000
Cash and cash equivalents at end of period 59,520,000 97,652,000
Supplemental disclosure of cash flow information:    
Cash paid for interest 85,000 0
Initial recognition of right of use asset 0 $ 1,700,000
Issuance of common stock under Equity Incentive Plans, value $ (864,000)