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v3.22.2.2

Consolidated Statements of Comprehensive Loss-Unaudited - USD ($) shares in Thousands, $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021
Revenues: |  |  |  |
Royalties and other revenue | $ 39 | $ 23 | $ 111 | $ 284
Stock-based compensation expense associated with research and development expense | 939 | 1,138 | 3,069 | 3,608
Operating expenses: |  |  |  |
Research and development, including stock-based compensation of $939, $1,138, $3,069 and $3,608 respectively | 10,557 | 15,682 | 38,839 | 38,548
Selling, general and administrative, including stock-based compensation of $1,709, $1,574, $5,183 and $4,741 respectively | 12,577 | 7,303 | 31,754 | 23,496
Total operating expenses | (23,134) | 22,985 | 70,593 | 62,044
Loss from operations | (23,095) | (22,962) | (70,482) | (61,760)
Interest expense | (864) | (171) | (1,677) | (507)
Interest and other income, net | 572 | 11 | 709 | 120
Net loss | $ (23,387) | $ (23,122) | $ (71,450) | $ (62,147)
Net income (loss) per common share, Basic | $ (0.13) | $ (0.16) | $ (0.45) | $ (0.43)
Shares used in computing net loss per common share, Basic | 174,904 | 145,820 | 157,984 | 144,558
Unrealized gain on investments |  | $ 0 |  |
Unrealized gain on investments | $ (341) | (1) | $ (481) | $ 1
Comprehensive loss | $ (23,728) | $ (23,122) | $ (71,931) | $ (62,146)

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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 912 -SubTopic 730 -Section 25 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=6472174&loc=d3e58812-109433 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 985 -SubTopic 20 -Section 50 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 730 -SubTopic 10 -Section 50 -Paragraph 1 -URI https://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373 + Details
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