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Statements of Comprehensive Loss Parentheticals (Parentheticals) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Stock-based compensation expense associated with research and development expense | $ 4,253 | $ 4,284 | $ 6,376
Stock-based compensation expense associated with general and administrative expense | $ 7,267 | $ 6,293 | $ 6,898

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- Definition Stock-based compensation expense associated with general and administrative expense. + References No definition available. + Details
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Namespace Prefix: | lxrx_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration

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- Definition Stock-based compensation expense included in research and development expense. + References No definition available. + Details
Name: | lxrx_StockBasedCompensationExpenseAssociatedWithResearchAndDevelopmentExpense
Namespace Prefix: | lxrx_
Data Type: | xbrli:monetaryItemType
Balance Type: | debit
Period Type: | duration