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Debt Obligations - Narrative (Details) - USD ($) | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | ---
Aug. 31, 2018 | Nov. 30, 2014 | Dec. 31, 2022 | Dec. 31, 2027 | Dec. 31, 2026 | Dec. 31, 2025 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020 | Jun. 30, 2022 | Mar. 31, 2022 | Aug. 30, 2018 | Dec. 18, 2017
Debt Instrument |  |  |  |  |  |  |  |  |  |  |  |  |
Proceeds from Convertible Debt |  | $ 87,500,000 |  |  |  |  |  |  | $ 75,800,000 |  |  |  |
Convertible Debt Instrument Interest Rate Stated Percentage |  |  | 5.25% |  |  |  | 5.25% |  |  |  |  |  |
Debt instrument, term | 2 years |  |  |  |  |  |  |  |  |  |  |  |
Recognition of gain or loss on extinguishment | $ 0 |  |  |  |  |  | $ 0 | $ 0 | 1,003,000 |  |  |  |
Estimated useful life of assets | 10 years |  |  |  |  |  |  |  |  |  |  |  |
Debt Instrument, Interest Rate, Stated Percentage |  |  | 7.90% |  |  |  | 7.90% |  |  |  |  |  |
Debt Instrument, Face Amount |  |  |  |  |  |  |  |  |  |  |  |  | $ 150,000,000
Convertible Debt |  |  |  |  |  |  |  | 11,600,000 |  |  |  |  |
Convertible Debt Exchange - Total cash consideration |  |  |  |  |  |  |  |  | $ 50,000,000 |  |  |  |
2020 Convertible debt exchange - share payment total |  |  |  |  |  |  |  |  | 10,368,956 |  |  |  |
2020 convertible debt exchange - percentage of principal |  |  |  |  |  |  |  |  | 85.00% |  |  |  |
2020 convertible debt exchange - accrued interest |  |  |  |  |  |  |  |  | $ 1,300,000 |  |  |  |
Convertible debt exchange |  |  |  |  |  |  |  |  | 9,600,000 |  |  |  |
Mortgage Debt Interest Rate_Base_Revere_LXRX |  |  |  |  |  |  |  |  |  |  |  | 5.50% |
Mortgage Debt Interest Rate BasePlus_Revere_LXRX |  |  |  |  |  |  |  |  |  |  |  | 7.50% |
Mortgage Debt Instrument_Revere_LXRX |  |  |  |  |  |  |  |  |  |  |  | $ 12,900,000 |
Mortgage Debt Balloon Payment_LXRX |  |  |  |  |  |  |  |  |  |  |  | $ 10,300,000 |
Long-Term Debt, Percentage Bearing Fixed Interest, Percentage Rate |  |  | 8.01% |  |  |  | 8.01% |  |  |  |  |  |
Term Loan A Warrant Exercise Price |  |  | $ 1.95 |  |  |  | $ 1.95 |  |  | $ 2.08 |  |  |
Subordinated Borrowing, Interest Rate |  |  | 12.04% |  |  |  |  |  |  |  |  |  |
Term Loan D Warrant % |  |  | 0.875% |  |  |  | 0.875% |  |  |  |  |  |
Term Loan A Final Payment |  |  | $ 1,500,000 |  |  |  | $ 1,500,000 |  |  |  |  |  |
Final Payment % with extention |  |  | 7.00% |  |  |  | 7.00% |  |  |  |  |  |
Final Payment % with no extention |  |  | 6.00% |  |  |  | 6.00% |  |  |  |  |  |
Term Loan A Debt Issuance Costs |  |  | $ 350,000 |  |  |  | $ 350,000 |  |  |  |  |  |
Oxford Facility Fee |  |  | 500,000 |  |  |  | 500,000 |  |  |  |  |  |
Term Loan A Net Cash Receipt |  |  | 24,150,000 |  |  |  | 24,150,000 |  |  |  |  |  |
Adjustments to Additional Paid in Capital, Warrant Issued |  |  | 300,000 |  |  |  | 700,000 |  |  |  |  |  |
Interest Expense |  |  |  |  |  |  | 2,780,000 | $ 802,000 | $ 14,544,000 |  |  |  |
Term Loan A Debt Discount |  |  | $ 4,400,000 |  |  |  | $ 4,400,000 |  |  |  |  |  |
Term Loan C Warrant % |  |  | 1.75% |  |  |  | 1.75% |  |  |  |  |  |
Term Loan A Warrants Number |  |  | 224,128 |  |  |  | 224,128 |  |  | 420,673 |  |  |
Term Loan A&B Warrant % |  |  | 3.50% |  |  |  | 3.50% |  |  |  |  |  |
Term Loan B |  |  | $ 25,000,000 |  |  |  | $ 25,000,000 |  |  |  |  |  |
2026 Oxford Principal Payments |  |  |  |  | $ 13,000,000 |  |  |  |  |  |  |  |
Oxford Loan Facility |  |  | 150,000,000 |  |  |  | 150,000,000 |  |  |  |  |  |
Oxford Amendment Fee |  |  | 300,000 |  |  |  | 300,000 |  |  |  |  |  |
Term Loan A |  |  |  |  |  |  |  |  |  |  | $ 25,000,000 |  |
Term Loan C |  |  | 50,000,000 |  |  |  | 50,000,000 |  |  |  |  |  |
Term Loan D |  |  | 50,000,000 |  |  |  | 50,000,000 |  |  |  |  |  |
Long-term Debt, Gross |  |  | 48,600,000 |  |  |  | 48,600,000 |  |  |  |  |  |
Long-Term Debt, Gross |  |  | $ (48,579,000) |  |  |  | $ (48,579,000) |  |  |  |  |  |
2027 Oxford Principal Payments A |  |  |  | $ 4,800,000 |  |  |  |  |  |  |  |  |
2025 Oxford Principal Payment A |  |  |  |  |  | $ 8,700,000 |  |  |  |  |  |  |
2025 Oxford Principal Payments B |  |  |  |  |  | $ 8,700,000 |  |  |  |  |  |  |
2026 Oxford Principal Payments B |  |  |  |  | $ 13,000,000 |  |  |  |  |  |  |  |
2027 Oxford Principal Payments B |  |  |  | $ 4,800,000 |  |  |  |  |  |  |  |  |
Debt, Weighted Average Interest Rate |  |  | 9.00% |  |  |  | 9.00% |  |  |  |  |  |
Term Loan B Net Cash Receipt |  |  | $ 24,960,000 |  |  |  | $ 24,960,000 |  |  |  |  |  |
Term Loan B Debt Discount |  |  | $ 40,000.00 |  |  |  | 40,000.00 |  |  |  |  |  |
Interest Expense, Interest-Bearing Liability |  |  |  |  |  |  | $ 2,800,000 |  |  |  |  |  |

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