Consolidated Statements of Comprehensive Loss Parentheticals - USD ($) $ in Thousands	3 Months Ended	6 Months Ended
Jun. 30, 2023	Jun. 30, 2022	Jun. 30, 2023	Jun. 30, 2022
Consolidated Statements of Operations [Abstract]
Stock-based compensation expense associated with research and development expense	$ 1,302	$ 1,098	$ 2,505	$ 2,130
Stock-based compensation expense associated with selling, general and administrative expense	$ 2,513	$ 1,734	$ 4,725	$ 3,474

Stock-based compensation expense associated with selling, general and administrative expense

No definition available.

Name:	lxrx_Stockbasedcompensationexpenseassociatedwithsellinggeneralandadministrativeexpense
Namespace Prefix:	lxrx_
Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration