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Consolidated Statements of Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Revenues:      
Net product revenue $ 1,110 $ 0 $ 0
Royalties and other revenue 94 139 298
Total revenues 1,204 139 298
Operating expenses:      
Cost of sales 85 0 0
Research and development, including stock-based compensation of $5,139, $4,253 and $4,284 respectively 58,887 52,816 55,046
Selling, general and administrative, including stock-based compensation of $9,201, $7,267 and $6,293, respectively 113,982 48,083 32,342
Total operating expenses 172,954 100,899 87,388
Loss from operations (171,750) (100,760) (87,090)
Other Expenses (13,101) (2,780) (802)
Interest income and other, net 7,732 1,596 134
Net loss $ (177,119) $ (101,944) $ (87,758)
Net loss per common share, basic (usd per share) $ (0.80) $ (0.62) $ (0.60)
Net loss per common share, diluted (usd per share) $ (0.80) $ (0.62) $ (0.60)
Shares used in computing net loss per common share, basic 221,130 165,733 145,652
Shares used in computing net loss per common share, diluted 221,130 165,733 145,652
Other comprehensive loss:      
Unrealized gain (loss) on investments $ 459 $ (418) $ (4)
Comprehensive loss $ (176,660) $ (102,362) $ (87,762)