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Segment Information - Schedule of Segment Reporting Information (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Segment Reporting Information [Line Items] |  |  |
Net product revenue | $ 6,001 | $ 1,110 | $ 0
Licensing revenue | 25,000 | 0 | 0
Royalties and other revenue | 80 | 94 | 139
Total revenues | 31,081 | 1,204 | 139
Cost of sales | 616 | 85 | 0
Research and development | 84,480 | 58,887 | 52,816
Severance costs |  | 0 | 0
Total operating expenses | 228,198 | 172,954 | 100,899
Loss from operations | (197,117) | (171,750) | (100,760)
Interest and other expense | (15,579) | (13,101) | (2,780)
Interest income and other, net | 12,293 | 7,732 | 1,596
Net loss | (200,403) | (177,119) | (101,944)
Stock-based compensation | 13,500 | 14,300 | 11,500
Research and Development Expense |  |  |
Segment Reporting Information [Line Items] |  |  |
Severance costs | 1,100 |  | 300
Stock-based compensation | 5,839 | 5,139 | 4,253
Selling and Marketing Expense |  |  |
Segment Reporting Information [Line Items] |  |  |
Severance costs | 9,300 | 1,400 |
Stock-based compensation | 2,000 | 2,300 | 500
General and Administrative Expense |  |  |
Segment Reporting Information [Line Items] |  |  |
Severance costs | 1,900 | 40 |
Stock-based compensation | 5,700 | 6,900 | 6,800
Reportable Segment |  |  |
Segment Reporting Information [Line Items] |  |  |
Net product revenue | 6,001 | 1,110 | 0
Licensing revenue | 25,000 | 0 | 0
Royalties and other revenue | 80 | 94 | 139
Total revenues | 31,081 | 1,204 | 139
Cost of sales | 616 | 85 | 0
Research and development | 77,549 | 53,748 | 48,268
Sales and marketing | 97,265 | 77,561 | 19,166
General and administrative | 26,991 | 25,786 | 21,649
Other segment expense (1) (2) | 25,777 | 15,774 | 11,816
Total operating expenses | 228,198 | 172,954 | 100,899
Loss from operations | (197,117) | (171,750) | (100,760)
Interest and other expense | (15,579) | (13,101) | (2,780)
Interest income and other, net | 12,293 | 7,732 | 1,596
Net loss | $ (200,403) | $ (177,119) | $ (101,944)

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