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Equity Incentive Awards (Tables)
12 Months Ended
Dec. 31, 2024
Share-Based Payment Arrangement [Abstract]  
Summary of Stock Option Activity
Stock Options. The following is a summary of stock option activity under Lexicon’s equity incentive plans for the year ended December 31, 2024:

 As of December 31, 2024
(in thousands, except exercise price data)OptionsWeighted Average Exercise Price
Outstanding at beginning of year18,705 $3.93 
Granted7,377 1.92 
Exercised(51)1.72 
Expired(296)11.79 
Forfeited(10,346)3.36 
Outstanding at end of year15,389 3.20 
Exercisable at end of year7,518 $4.33 
Summary of Weighted-Average Stock Options Assumptions The following weighted-average assumptions were used for stock options granted in the years ended December 31, 2024, 2023 and 2022, respectively:
 Expected VolatilityRisk-free Interest RateExpected TermDividend
Rate
December 31, 2024:    
Employees96%4.4%4%
Officers and non-employee directors104%4.2%6%
December 31, 2023:
Employees110%3.9%4%
Officers and non-employee directors98%4.0%6%
December 31, 2022:
Employees109%2.8%4%
Officers and non-employee directors91%1.9%7%
Summary of Restricted Stock Units Activity
The following is a summary of restricted stock units activity under Lexicon’s stock-based compensation plans for the year ended December 31, 2024:

 SharesWeighted Average Grant Date Fair Value
 (in thousands) 
Outstanding at December 31, 20235,015 $2.78 
Granted8,527 2.14 
Vested(1,970)3.10 
Forfeited(5,272)2.23 
Outstanding at December 31, 20246,300 $2.27