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Segment Information - Schedule of Segment Reporting Information (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Segment Reporting Information [Line Items]      
Net product revenue $ 6,001 $ 1,110 $ 0
Licensing revenue 25,000 0 0
Royalties and other revenue 80 94 139
Total revenues 31,081 1,204 139
Cost of sales 616 85 0
Research and development 84,480 58,887 52,816
Severance costs   0 0
Total operating expenses 228,198 172,954 100,899
Loss from operations (197,117) (171,750) (100,760)
Interest and other expense (15,579) (13,101) (2,780)
Interest income and other, net 12,293 7,732 1,596
Net loss (200,403) (177,119) (101,944)
Stock-based compensation 13,500 14,300 11,500
Research and Development Expense      
Segment Reporting Information [Line Items]      
Severance costs 1,100   300
Stock-based compensation 5,839 5,139 4,253
Selling and Marketing Expense      
Segment Reporting Information [Line Items]      
Severance costs 9,300 1,400  
Stock-based compensation 2,000 2,300 500
General and Administrative Expense      
Segment Reporting Information [Line Items]      
Severance costs 1,900 40  
Stock-based compensation 5,700 6,900 6,800
Reportable Segment      
Segment Reporting Information [Line Items]      
Net product revenue 6,001 1,110 0
Licensing revenue 25,000 0 0
Royalties and other revenue 80 94 139
Total revenues 31,081 1,204 139
Cost of sales 616 85 0
Research and development 77,549 53,748 48,268
Sales and marketing 97,265 77,561 19,166
General and administrative 26,991 25,786 21,649
Other segment expense (1) (2) 25,777 15,774 11,816
Total operating expenses 228,198 172,954 100,899
Loss from operations (197,117) (171,750) (100,760)
Interest and other expense (15,579) (13,101) (2,780)
Interest income and other, net 12,293 7,732 1,596
Net loss $ (200,403) $ (177,119) $ (101,944)