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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Cash flows from operating activities:      
Net loss $ (200,403) $ (177,119) $ (101,944)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 534 554 427
Stock-based compensation 13,499 14,340 11,520
Amortization of debt-related costs 1,845 1,774 741
Loss on disposal of property and equipment 0 0 3
Accretion of marketable securities purchased at a discount (9,305) (5,617) 0
Other non-cash adjustments 812 1,512 0
Changes in operating assets and liabilities:      
Increase in accounts receivable (2,463) (982) (14)
Decrease (increase) in inventories 150 (381) 0
Decrease (increase) in prepaid expenses and other current assets 598 (2,899) (316)
Decrease in other long-term assets 1,152 467 656
Increase in accounts payable and other liabilities 14,801 6,454 76
Net cash used in operating activities (178,780) (161,897) (88,851)
Cash flows from investing activities:      
Purchases of property and equipment (1,031) (470) (1,326)
Purchases of investments (328,747) (223,343) (133,949)
Maturities of investments                                                                                        314,400 173,870 64,197
Net cash used in investing activities (15,378) (49,943) (71,078)
Cash flows from financing activities:      
Proceeds from issuance of common stock, net of fees 0 138,823 94,205
Proceeds from issuance of common stock for equity incentive plans 64 0 0
Proceeds from issuance of preferred stock, net of fees 241,322 0 0
Repurchase of common stock (1,730) (824) (864)
Proceeds from debt borrowings, net of fees 0 49,961 48,868
Other debt financing fees (1,307) 0 0
Net cash provided by financing activities 238,349 187,960 142,209
Net increase (decrease) in cash and cash equivalents 44,191 (23,880) (17,720)
Cash and cash equivalents at beginning of year                                              22,465 46,345 64,065
Cash and cash equivalents at end of year                                                                           66,656 22,465 46,345
Supplemental disclosure of cash flow information:      
Cash paid for interest 12,919 10,057 2,289
Supplemental disclosure of noncash investing and financing activities:      
Right-of-use assets obtained in exchange for operating lease liability 0 0 5,206
Issuance of equity-classified warrants 0 307 1,030
Issuance of treasury stock 0 0 6,321
Accrual of deferred financing costs 0 250 0
Conversion of preferred stock to common stock $ 115 $ 0 $ 0